Optimization of the Process of Gelatin-ceftiofur Sodium Microspheres

武汉理工大学学报-材料科学版(英文版), 2010, 25(6): 975-978. doi: 10.1007/s11595-010-0132-x

^1, , ^2, , ^3, , ^4, , ^5, , ^6, , ^7, , ^8,

1.Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China;Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

2.Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

3.Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China

4.Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China

5.Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

6.Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

7.Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

8.Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China

Optimization of the Process of Gelatin-ceftiofur Sodium Microspheres

HAO Zhihui ^1, , WANG Yanling ^2, , TANG Shusheng ^3, , WANG Gang ^4, , MEI Qiu ^5, , ZHANG Ruili ^6, , LIU Yuanyuan ^7, , XIAO Xilong ^8,

1.Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China;Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

2.Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

3.Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China

4.Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China

5.Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

6.Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

7.Qingdao KDN Animal Drugs Technology Development Research Center, Qingdao 266061, China

8.Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China

Keywords： gelatin microspheres

参考文献

[1]	Izutsu,K;Kojima,S .Freeze-concentration separates proteins and polymer excipients into different amorphous phases.[J].Pharmaceutical research,2000(10):1316-1322.
[2]	Gautier H.;Caillon J. .Influence of isostatic compression on the stability of vancomycin loaded with a calcium phosphate-implantable drug delivery device[J].Journal of biomedical materials research, Part B. Applied biomaterials,2000(2):308-314.
[3]	Nurkeeva ZS;Khutoryanskiy VV;Mun GA;Sherbakova MV;Ivaschenko AT;Aitkhozhina NA .Polycomplexes of poly(acrylic acid) with streptomycin sulfate and their antibacterial activity.[J].European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V,2004(2):245-249.

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