改进了1-丁基-3-甲基咪唑L-脯氨酸([bmim][Pro])功能化离子液体的合成路线,并将该离子液体用于催化含活泼亚甲基化合物与醛或酮的Knoevenagel缩合反应.在水介质中,室温下,该离子液体可快速催化上述Knoevenagel缩合反应,并选择性生成α,β-不饱和羰基化合物且分离收率可达到88％～97％.该脯氨酸离子液体循环重复使用6次后,催化活性没有明显的下降.此外,初步探讨了其催化过程机理.
The pyrrolidinecarboxylic functionalized ionic liquid,1-butyl-3-methylimidazolium-(S)-2-pyrrolidinecarboxylic acid salt ([bmim][Pro]),was prepared using an improved procedure.a,β-Unsaturated carbonyl compounds were selectively synthesized and high yields (88％-97％) were obtained at room temperature in aqueous media when [bmim][Pro] was used as the catalyst for the Knoevenagel reaction between a methylene compound and an aldehyde or ketone.[bmim][Pro] was reused six times without loss of catalytic activity.The catalytic mechanism is briefly discussed.
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