在金纳米粒子(AuNPs)上经苯硫酚衍生物(3,4二羟基苯基-偶氮-苯硫酚, DAT)自组装制得了一种新型纳米复合物,用于修饰玻璃碳电极(GCE/AuNP-DAT).采用循环伏安法研究了该新型电极的性质,并将其用作异丙肾上腺素(IP)电催化剂,考察了该纳米复合物的电催化活性,从而得到反应机理和催化反应速率常数.由于GCE/AuNP-DAT电极对尿酸氧化没有电催化活性,因此可将IP的氧化信号从该改进电极中分离出来,从而排除了尿酸对IP测定的干扰.该电极可作为传感器,当用于差动脉冲伏安法测定IP时,线性动态范围为1.0–1500.0μmol/L,检测极限为0.46μmol/L.
A novel nanocomposite (GCE/AuNP-DAT) was fabricated via the self-assembly of a thiophenol de-rivative (3,4-dihydroxyphenyl-azo-2-thiophenol, DAT) on a gold nanoparticle (AuNP)-modified glassy carbon electrode (GCE). This novel modified electrode was investigated using cyclic voltam-metry, and the electrode was applied for the electrocatalysis of isoproterenol (IP). The electrocata-lytic activity of this nanocomposite was studied, and the reaction mechanism and catalytic rate constant were determined for IP. The GCE/AuNP-DAT did not show any electrocatalytic activity for the oxidation of uric acid, and the oxidation signal for IP was therefore not affected by the presence of uric acid at this electrode;any interference from uric acid in the detection of IP was eliminated by the modified electrode. This electrode was applied as a sensor, and differential pulse voltammetry data obtained using this sensor exhibited a linear dynamic range of 1–1500 μmol/L and a detection limit of 0.46 μmol/L for IP.
参考文献
| [1] | Raoof J B;Hosseini S R;Mousavi-Sani S Z .[J].催化学报,2015,36:216. |
| [2] | Mazloum-Ardakani, M.;Sheikh-Mohseni, M.A.;Mirjalili, B.-F. .Selective and simultaneous voltammetric determination of glutathione, uric acid and penicillamine by a modified carbon nanotube paste electrode[J].Electroanalysis,2013(8):2021-2029. |
| [3] | Mazloum-Ardakani, M.;Beitollahi, H.;Amini, M.K.;Mirkhalaf, F.;Mirjalili, B.-F.;Akbari, A. .Application of 2-(3,4-dihydroxyphenyl)-1,3-dithialone self-assembled monolayer on gold electrode as a nanosensor for electrocatalytic determination of dopamine and uric acid[J].The Analyst: The Analytical Journal of the Royal Society of Chemistry: A Monthly International Publication Dealing with All Branches of Analytical Chemistry,2011(9):1965-1970. |
| [4] | Hu GZ;Zhang DP;Wu WL;Yang ZS .Selective determination of dopamine in the presence of high concentration of ascorbic acid using nano-Au self-assembly glassy carbon electrode[J].Colloids and Surfaces, B. Biointerfaces,2008(2):199-205. |
| [5] | Li J;Lin X Q .[J].Sens Actuators B,2007,124:486. |
| [6] | Goyal R N;Gupta V K;Oyama M;Bachheti N .[J].Talanta,2007,72:976. |
| [7] | Goyal R N;Aliumar A;Oyama M .[J].J Electroanal Chem,2009,631:58. |
| [8] | Luczak T .[J].Electrochim Acta,2009,54:5863. |
| [9] | Mashhadizadeh, M.H.;Ramezani, S.;Ebrahimi, S. .Potentiometric determination of nanomolar concentration of Cu (II) using a carbon paste electrode modified by a self-assembled mercapto compound on gold nanoparticles[J].Sensors and Actuators, B. Chemical,2012(1):305-311. |
| [10] | Stryer L.Biochemistry[M].New York:Freeman,1988 |
| [11] | Voet J G;Voet D.Biochemistry[M].New York:Wiley,1995 |
| [12] | Lupetti K O;Vieira I C;Fatibello-Filho O .[J].Talanta,2002,57:135. |
| [13] | Alberts G;Lameris T;Van den Meiracker A H;Man int Veld A J,Boomsma F .[J].J Chromatogr B,1999,730:213. |
| [14] | Yamaguchi M.;Yoshimura M.;Ishida J. .Simultaneous determination of urinary catecholamines and 5-hydroxyindoleamines by high-performance liquid chromatography with fluorescence detection[J].The Analyst: The Analytical Journal of the Royal Society of Chemistry: A Monthly International Publication Dealing with All Branches of Analytical Chemistry,1998(2):307-311. |
| [15] | Qu Y;Moons L;Vandesande F .[J].J Chromatogr B,1997,704:351. |
| [16] | Zhou G J;Zhang G F;Chen H Y .[J].Anal Chim Acta,2002,463:257. |
| [17] | Mazloum-Ardakani M;Naser-Sadrabadi A;Sheikh-Mohseni M A;Naeimi H,Benvidi A,Khoshroo A .[J].J Electroanal Chem,2013,705:75. |
| [18] | Ensafi, A.A.;Dadkhah, M.;Karimi-Maleh, H. .Determination of isoproterenol and uric acid by voltammetric method using carbon nanotubes paste electrode and p-chloranil[J].Colloids and Surfaces, B. Biointerfaces,2011(1):148-154. |
| [19] | Mbouguen, J.C.K.;Kenfack, I.T.;Walcarius, A.;Ngameni, E. .Electrochemical response of ascorbic and uric acids at organoclay film modified glassy carbon electrodes and sensing applications[J].Talanta: The International Journal of Pure and Applied Analytical Chemistry,2011(1):754-762. |
| [20] | Yu J H;Wang S M;Ge L;Ge S G .[J].Biosens Bioelectron,2011,26:3284. |
| [21] | Zhao J X .[J].Biomed Chromatogr,2015,29:410. |
| [22] | Xie Y L;Yuan J;Ye H L;Song P,Hu S Q .[J].J Electroanal Chem,2015,749:26. |
| [23] | Zhao L L;Blackburn J;Brosseau C L .[J].Anal Chem,2015,87:441. |
| [24] | Mazloum-Ardakani M;Abolhasani M;Mirjalili B B F;Sheikh-Mohseni M A,Dehghani-Firouzabadi A,Khoshroo A .[J].催化学报,2014,35:201. |
| [25] | Ojani R;Raoof J B;Maleki A A;Safshekan S .[J].催化学报,2014,35:423. |
| [26] | Mazloum-Ardakani M;Dehghani-Firouzabadi A;Sheikh-Mohseni M A;Benvidi A,Mirjalili B B F,Zare R .[J].Measurement,2015,62:88. |
| [27] | Lee P C;Meisel D .[J].J Phys Chem,1982,86:3391. |
| [28] | Bard A J;Faulkner L R.Electrochemical Methods:Fundamentals and Applications[M].New York:Wiley,2000 |
| [29] | Duwez A S .[J].J Electron Spectrosc Relat Phenom,2004,134:97. |
| [30] | Wang Q;Jiang N;Li N Q .[J].Microchem J,2001,68:77. |
| [31] | Galus Z.Fundamentals of Electrochemical Analysis[M].New York:Ellis Horwood,1976 |
| [32] | Ensafi A A;Bahrami H;Karimi-Maleh H;Mallakpour S .[J].催化学报,2012,33:1919. |
| [33] | Gan J N;Cai Z;He X L;Qiu X L,Yue W C .[J].分析化学,2012,40:1877. |
| [34] | Kutluay A;Aslanoglu M .[J].Acta Chim Slov,2010,57:157. |
| [35] | Li X;Chen M F;Sun Z X .[J].郑州大学学报(理学版),2009,41:74. |
| [36] | Bonifacio VG;Marcolino LH;Teixeira MFS;Fatibello-Filho O .Voltammetric determination of isoprenaline in pharmaceutical preparations using a copper(II) hexacyanoferrate(III) modified carbon paste electrode[J].Microchemical Journal: Devoted to the Application of Microtechniques in all Branches of Science,2004(1):55-59. |
- 下载量()
- 访问量()
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%