以共混法制备了鸡毛角蛋白/淀粉复合膜,并对复合膜的力学性能进行了测试.研究表明:增塑剂(丙三醇)和淀粉的质量比可改变复合膜的力学性能.鸡毛角蛋白的加入可增加淀粉膜的抗张强度和断裂伸长率,当鸡毛角蛋白/淀粉的质量比为0.15时,复合膜的力学性能良好,吸水百分率小,抗水性较好,可适用于碱性物质的包装.不同pH条件下,鸡毛角蛋白/淀粉复合膜对罗丹明B具有不同的控制释放性能,因此有望作为一种新型的pH敏感的药物载体材料.
参考文献
| [1] | Dixit, RP;Puthli, SP .Oral strip technology: Overview and future potential[J].Journal of Controlled Release: Official Journal of the Controlled Release Society,2009(2):94-107. |
| [2] | Owens DE 3rd;Peppas NA .Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles.[J].International Journal of Pharmaceutics,2006(1):93-102. |
| [3] | Bonferoni MC;Chetoni P;Giunchedi P;Rossi S;Ferrari F;Burgalassi S;Caramella C .Carrageenan-gelatin mucoadhesive systems for ion-exchange based ophthalmic delivery: in vitro and preliminary in vivo studies.[J].European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V,2004(3):465-472. |
| [4] | Ismail Dogan Gunbas;Umran Aydemir Sezer;Sultan Gulce iz .Semi-IPN Chitosan/PEG Microspheres and Films for Biomedical Applications: Characterization and Sustained Release Optimization[J].Industrial & Engineering Chemistry Research,2012(37):11946-11954. |
| [5] | Altinisik, A.;Yurdakoc, K. .Synthesis, characterization, and enzymatic degradation of chitosan/PEG hydrogel films[J].Journal of Applied Polymer Science,2011(3):1556-1563. |
| [6] | Javanmard M;Ahangari R;Tavakolipour H .Effects of wheat starch edible films on rancidity and moisture uptake of pistachio kemels as a new package[J].Journal of Food Process Engineering,2011,34(04):1156. |
| [7] | Jun-Feng Su;Zhen Huang;Xiao-Yan Yuan .Structure and properties of carboxymethyl cellulose/soy protein isolate blend edible films crosslinked by Maillard reactions[J].Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides,2010(1):145-153. |
| [8] | 姜燕,马中苏,张海悦.蛋白质基可食性生物聚合膜的研究进展[J].食品研究与开发,2011(11):168-172. |
| [9] | S.M. Ojagh;R. Nunez-Flores;M.E. Lopez-Caballero;M.P. Montero;M.C. Gomez-Guillen .Lessening of high-pressure-induced changes in Atlantic salmon muscle by the combined use of a fish gelatin-lignin film[J].Food Chemistry,2011(2):595-606. |
| [10] | Xin-Yi Dai;Wei Nie;Yong-Chun Wang;Yi Shen;Yan Li;Shu-Jie Gan .Electrospun emodin polyvinylpyrrolidone blended nanofibrous membrane: a novel medicated biomaterial for drug delivery and accelerated wound healing[J].Journal of Materials Science. Materials in Medicine,2012(11):2709-2716. |
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