壳聚糖微球的制备及其对防污剂Sea-Nine 211缓释性能的研究

材料导报, 2014, 28(24): 30-46. doi: 10.11896/j.issn.1005-023X.2014.24.008

壳聚糖微球的制备及其对防污剂Sea-Nine 211缓释性能的研究

曹京宜 ^1, , 孟宪林 ^2, , 张海永 ^3, , 侯梦洁 ^4, , 夏俊华 ^5, , 陈蓉蓉 ^6, , 王乐乐 ^7, , 王君 ^8, , 刘连河 ^9,

1.91872部队海军涂料分析检测中心,北京,102442

2.91872部队海军涂料分析检测中心,北京,102442

3.91872部队海军涂料分析检测中心,北京,102442

4.哈尔滨工程大学海洋先进材料研究院,哈尔滨,150001

5.哈尔滨工程大学海洋先进材料研究院,哈尔滨,150001

6.哈尔滨工程大学海洋先进材料研究院,哈尔滨,150001

7.哈尔滨工程大学海洋先进材料研究院,哈尔滨,150001

8.哈尔滨工程大学海洋先进材料研究院,哈尔滨,150001

9.哈尔滨工程大学海洋先进材料研究院,哈尔滨150001;青岛海洋新材料科技有限公司,青岛266100

基金项目: 科技部国家国际合作专项(2013DFA50480) 总装预研基金

关键词：壳聚糖微球 , 乳化交联法 , 包覆率 , 缓释 , Sea-Nine 211

Preparation of Chitosan Microspheres and Their Controlled Release Performance While Loaded with Sea-Nine 211

Keywords： chitosan microspheres , emulsion crosslinking method , cladding rate , controlled release , Sea-Nine 211

采用乳化交联法中的复乳法(o/w/o型)制备负载Sea-Nine 211的壳聚糖(CS)微球,并用扫描电镜和红外光谱对其结构及形貌进行了表征.应用正交试验设计,考察了壳聚糖浓度、投料比、交联剂浓度对微球制备的影响.载有疏水性防污剂Sea-Nine 211的壳聚糖微球的包覆率和缓释性能都比较良好,缓释的防污剂对海洋硅藻三角褐指藻的生长有抑制作用.

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