荧光传感器具有灵敏度高、专一性强、样品处理简易及操作过程方便、响应速度快、可用于体内和体外成像研究等优点，颇受人们的青睐。在新型荧光传感器的设计中，传感器识别单元与信号报告单元之间的传感机制一直受到人们的广泛关注。随着超分子科学的发展，一些新型的传感机制被应用于传感器的设计中。其中，基于激发态分子内质子转移(ESIPT)机理的荧光传感器通常具有发光强、斯托克斯位移较大、光稳定性好等优异特性，表现出良好的传感性能。综述了 ESIPT 这种新型的荧光传感机制的研究进展，包括此传感机制的基本原理，其在荧光传感器设计中的应用，并展望了该领域的发展趋势。
Fluorescent probes are gaining more and more attention because of their high sensitivity,specificity, simplicity of implementation,and fast response times,offering application methods not only for in vitro assays but al-so for in vivo imaging studies.In terms of the design of novel fluorescent chemosensor,the exploration of new mecha-nisms of interaction between recognition and signal reporting units acquires continuing interest.With the rapid deve-lopment of supramolecular chemistry,a variety of new design principles have been applied in fluorescent sensing re-cently.Among these new emerging signaling mechanisms,excited-state intramolecular proton transfer (ESIPT)-based fluorescent probes generally display excellent sensing performance for the virtues of intense luminescence,large Stokes shifts as well as good photostability.Herein,the research progress in this novel signaling approach is summarized,in-cluding the sensing mechanism,its application in the design of chemosensors as well as the development trend.
参考文献
- 下载量()
- 访问量()
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%