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石墨烯是处于蜂窝状晶体点阵上的碳原子以sp2杂化链接形成的单原子层二维晶体,因独特的结构及优异的性能而备受关注,并在复合材料、纳米电子器件、能量储存和转换、液晶显示等众多领域具有重要的应用前景.主要介绍石墨烯类材料在疾病诊断和治疗方面的应用研究,包括生物分子检测、生物成像等诊断检测和药物载体、光动力治疗等肿瘤治疗方面的应用,并展望了其在生物医学领域的发展前景.

参考文献

[1] Novoselov K S;Geim A K;Morozov S V et al.Electric field effect in atomically thin carbon films[J].SCIENCE,2004,306(5696):666.
[2] Novoselov K S;Geim A K;Morozov S V et al.Two-dimensional gas of massless Dirac fermions in graphene[J].NATURE,2005,438(7065):197.
[3] Chen, F;Xia, JL;Ferry, DK;Tao, NJ .Dielectric Screening Enhanced Performance in Graphene FET[J].Nano letters,2009(7):2571-2574.
[4] Zhou D;Cui Y;Han B .Graphene-based hybrid materials and their applications in energy storage and conversion[J].Chinese Science Bulletin,2012,57(23):2983.
[5] Ostrikov, K.;Neyts, E.C.;Meyyappan, M. .Plasma nanoscience: From nano-solids in plasmas to nano-plasmas in solids[J].Advances in physics,2013(2):113-224.
[6] Robinson, J.T.;Tabakman, S.M.;Liang, Y.;Wang, H.;Sanchez Casalongue, H.;Vinh, D.;Dai, H. .Ultrasmall reduced graphene oxide with high near-infrared absorbance for photothermal therapy[J].Journal of the American Chemical Society,2011(17):6825-6831.
[7] Ryoo, S.-R.;Kim, Y.-K.;Kim, M.-H.;Min, D.-H. .Behaviors of NIH-3T3 fibroblasts on graphene/carbon nanotubes: Proliferation, focal adhesion, and gene transfection studies[J].ACS nano,2010(11):6587-6598.
[8] Li Y;Liu Y;Fu Y;Wei T;Le Guyader L;Gao G;Liu RS;Chang YZ;Chen C .The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways.[J].Biomaterials,2012(2):402-411.
[9] Liopo AV;Stewart MP;Hudson J;Tour JM;Pappas TC .Biocompatibility of native and functionalized single-walled carbon nanotubes for neuronal interface[J].Journal of nanoscience and nanotechnology,2006(5):1365-1374.
[10] Guangbo Qu,Xiaoyan Wang,Qian Liu,Rui Liu,Nuoya Yin,Juan Ma,Liqun Chen.The ex vivo and in vivo biological performances of graphene oxide and the impact of surfactant on graphene oxide's biocompatibility[J].环境科学学报(英文版),2013(05):873-881.
[11] Miao,W.;Shim,G.;Lee,S.;Choe,Y.S.;Oh,Y.-K. .Safety and tumor tissue accumulation of pegylated graphene oxide nanosheets for co-delivery of anticancer drug and photosensitizer[J].Biomaterials,2013(13):3402-3410.
[12] Li N;Zhang X;Song Q;Su R;Zhang Q;Kong T;Liu L;Jin G;Tang M;Cheng G .The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates.[J].Biomaterials,2011(35):9374-9382.
[13] Tang, Z.;Wu, H.;Cort, J.R.;Buchko, G.W.;Zhang, Y.;Shao, Y.;Aksay, I.A.;Liu, J.;Lin, Y. .Constraint of DNA on functionalized graphene improves its biostability and specificity[J].Small,2010(11):1205-1209.
[14] Chun-Hua Lu;Huang-Hao Yang;Chun-Ling Zhu .A Graphene Platform for Sensing Biomolecules[J].Angewandte Chemie,2009(26):4785-4787.
[15] He, Q.;Sudibya, H.G.;Yin, Z.;Wu, S.;Li, H.;Boey, F.;Huang, W.;Chen, P.;Zhang, H. .Centimeter-long and large-scale micropatterns of reduced graphene oxide films: Fabrication and sensing applications[J].ACS nano,2010(6):3201-3208.
[16] Qingsong Mei;Zhongping Zhang .Photoluminescent Graphene Oxide Ink to Print Sensors onto Microporous Membranes for Versatile Visualization Bioassays[J].Angewandte Chemie,2012(23):5602-5606.
[17] Lim, S.Y.;Ahn, J.;Lee, J.S.;Kim, M.-G.;Park, C.B. .Graphene-oxide-based immunosensing through fluorescence quenching by peroxidase-catalyzed polymerization[J].Small,2012(13):1994-1999.
[18] Peng, C.;Hu, W.;Zhou, Y.;Fan, C.;Huang, Q. .Intracellular imaging with a graphene-based fluorescent probe[J].Small,2010(15):1686-1692.
[19] Gollavelli,G.;Ling,Y.-C. .Multi-functional graphene as an invitro and invivo imaging probe[J].Biomaterials,2012(8):2532-2545.
[20] Yang, K.;Zhang, S.;Zhang, G.;Sun, X.;Lee, S.-T.;Liu, Z. .Graphene in mice: Ultrahigh in vivo tumor uptake and efficient photothermal therapy[J].Nano letters,2010(9):3318-3323.
[21] Liu Z;Robinson JT;Sun XM;Dai HJ .PEGylated nanographene oxide for delivery of water-insoluble cancer drugs[J].Journal of the American Chemical Society,2008(33):10876-10877.
[22] Sun X;Liu Z et al.Nano-graphene oxide for cellular imaging and drug delivery[J].Nano Res,2008,1:203.
[23] Dembereldorj U;Kim M;Kim S et al.A spatiotemporal anticancer drug release platform of PEGylated graphene oxide triggered by glutathione in vitro and in vivo[J].Journal of Materials Chemistry,2012,22(48):23845.
[24] Depan, D.;Shah, J.;Misra, R.D.K. .Controlled release of drug from folate-decorated and graphene mediated drug delivery system: Synthesis, loading efficiency, and drug release response[J].Materials science & engineering, C. Biomimetic and supramolecular systems,2011(7):1305-1312.
[25] Wen, H.;Dong, C.;Dong, H.;Shen, A.;Xia, W.;Cai, X.;Song, Y.;Li, X.;Li, Y.;Shi, D. .Engineered redox-responsive PEG detachment mechanism in PEGylated nano-graphene oxide for intracellular drug delivery[J].Small,2012(5):760-769.
[26] Yang, Y.;Zhang, Y.-M.;Chen, Y.;Zhao, D.;Chen, J.-T.;Liu, Y. .Construction of a graphene oxide based noncovalent multiple nanosupramolecular assembly as a scaffold for drug delivery[J].Chemistry: A European journal,2012(14):4208-4215.
[27] Xiaoying Yang;Xiaoyan Zhang;Yanfeng Ma .Superparamagnetic graphene oxide-Fe3O4 nanoparticles hybrid for controlled targeted drug carriers[J].Journal of Materials Chemistry: An Interdisciplinary Journal dealing with Synthesis, Structures, Properties and Applications of Materials, Particulary Those Associated with Advanced Technology,2009(18):2710-2714.
[28] Zhang, LM;Xia, JG;Zhao, QH;Liu, LW;Zhang, ZJ .Functional Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Mixed Anticancer Drugs[J].Small,2010(4):537-544.
[29] Pan Y;Bao H;ct al .Water-soluble poly(N-isopropylacrylamide)-graphene sheets synthesized via click chemistry for drug delivery[J].Advanced Functional Materials,2011,21:2754.
[30] Xiujuan Fan;Guozheng Jiao;Lei Gao .The preparation and drug delivery of a graphene-carbon nanotube-Fe3O4 nanoparticle hybrid[J].Journal of Materials Chemistry, B. materials for biology and medicine,2013(20):2658-2664.
[31] Kunping Liu;Jing-Jing Zhang;Fang-Fang Cheng .Green and facile synthesis of highly biocompatible graphene nanosheets and its application for cellular imaging and drug delivery[J].Journal of Materials Chemistry: An Interdisciplinary Journal dealing with Synthesis, Structures, Properties and Applications of Materials, Particulary Those Associated with Advanced Technology,2011(32):12034-12040.
[32] Yunping Chen;Yuanyuan Qi;Xingbin Yan;Haibing Ma;Jiangtao Chen;Bin Liu;Qunji Xue .Green Fabrication of Porous Chitosan/Graphene Oxide Composite Xerogels for Drug Delivery[J].Journal of Applied Polymer Science,2014(6):40006-1-40006-11.
[33] Liangzhu Feng;huai Zhang;Zhuang Liu .Graphene based gene transfection[J].Nanoscale,2011(3):1252-1257.
[34] Zhang, L.;Lu, Z.;Zhao, Q.;Huang, J.;Shen, H.;Zhang, Z. .Enhanced chemotherapy efficacy by sequential delivery of siRNA and anticancer drugs using PEI-grafted graphene oxide[J].Small,2011(4):460-464.
[35] Bao, H.;Pan, Y.;Ping, Y.;Sahoo, N.G.;Wu, T.;Li, L.;Li, J.;Gan, L.H. .Chitosan-functionalized graphene oxide as a nanocarrier for drug and gene delivery[J].Small,2011(11):1569-1578.
[36] Zhou, L.;Wang, W.;Tang, J.;Zhou, J.-H.;Jiang, H.-J.;Shen, J. .Graphene oxide noncovalent photosensitizer and its anticancer activity in vitro[J].Chemistry: A European journal,2011(43):12084-12091.
[37] Tian, B.;Wang, C.;Zhang, S.;Feng, L.;Liu, Z. .Photothermally enhanced photodynamic therapy delivered by nano-graphene oxide[J].ACS nano,2011(9):7000-7009.
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