通过芘荧光探针研究了基于双丙酮丙烯酰胺(DAAM)的新型温敏大分子单体在溶液中的热缔合行为.结果表明,温敏大分单体的临界缔合浓度(CAC)取决于丙烯酰胺(AM)与DAAM的组成比.DAAM的比例越大,CAC就越低;随着温敏大分子单体中DAAM的含量、大分子单体浓度和溶液pH的增加,芘的I1/I3值降低,疏水缔合作用增强,且温度越高,I1/I3值越低,呈现明显的热缔合行为.温敏大分单体的热缔合行为随组成、浓度和pH变化的这种性质有可能在新型温敏聚合物及凝胶的合成设计上获得应用.
参考文献
| [1] | Gil E S;Hudson S M .Stimuli-responsive polymers and their bioconjugates[J].Progress in Polymer Science,2004,29(12):1173. |
| [2] | Ivaylo Dimitrov;Barbara Trzebicka;Axel H.E.Miiller .Thermosensitive water-soluble copolymers with doubly responsive reversibly interacting entities[J].Progress in Polymer Science,2007(11):1275-1343. |
| [3] | Liu F;Urban M W .Recent advances and challenges in designing stimuli-responsive polymers[J].Progress in Polymer Science,2010,35(1-2):3. |
| [4] | Yasushi Maeda;Tomoya Nakamura;Isao Ikeda .Changes in the Hydration States of Poly(N-alkylacrylamide)s during Their Phase Transitions in Water Observed by FTIR Spectroscopy[J].Macromolecules,2001(5):1391-1399. |
| [5] | Allcock HR.;Dudley GK. .LOWER CRITICAL SOLUBILITY TEMPERATURE STUDY OF ALKYL ETHER BASED POLYPHOSPHAZENES[J].Macromolecules,1996(4):1313-1319. |
| [6] | Zou, YQ;Brooks, DE;Kizhakkedathu, JN .A novel functional polymer with tunable LCST[J].Macromolecules,2008(14):5393-5405. |
| [7] | Idziak I.;Lessard D.;Gravel D.;Zhu X.X.;Avoce D. .Thermosensitivity of aqueous solutions of poly(N,N-diethylacrylamide)[J].Macromolecules,1999(4):1260-1263. |
| [8] | Kjφ niksen A L;Zhu K Z;Karlsson G et al.Novel transition behaviorin aqueous solutions of a changed thermoresponsive triblock copolymer[J].Colloid Surf A:Physicochem Eng Aspects,2009,333(1-3):32. |
| [9] | Cao ZQ;Liu WG;Gao P;Yao KD;Li HX;Wang GC .Toward an understanding of thermoresponsive transition behavior of hydrophobically modified N-isopropylacrylamide copolymer solution[J].Polymer: The International Journal for the Science and Technology of Polymers,2005(14):5268-5277. |
| [10] | Dilgimen AS;Mustafaeva Z;Demchenko M;Kaneko T;Osada Y;Mustafaev M .Water-soluble covalent conjugates of bovine serum albumin with anionic poly(N-isopropyl-acrylamide) and their immunogenicity.[J].Biomaterials,2001(17):2383-2392. |
| [11] | Stayton PS;Shimoboji T;Long C;Chilkoti A;Chen G;Harris JM;Hoffman AS .Control of protein-ligand recognition using a stimuli-responsive polymer.[J].Nature,1995(6556):472-474. |
| [12] | Ding Z;Fong R B;Long L J et al.Size-dependent control of the binding of biotinylated proteins to streptavidin using a polymer shield[J].NATURE,2001,411:59. |
| [13] | Huber DL.;Manginell RP.;Samara MA.;Kim BI.;Bunker BC. .Programmed adsorption and release of proteins in a microfluidic device[J].Science,2003(5631):352-354. |
| [14] | Kikuchi A;Okano T .Nanostructured designs of biomedical materials: Applications of cell sheet engineering to functional regenerative tissues and organs[J].Journal of Controlled Release: Official Journal of the Controlled Release Society,2005(1/3):69-84. |
| [15] | Steven Carter;Stephen Rimmer;Ramune Rutkaite;Linda Swanson;J.P.A.Fairclough .Highly Branched Poly(N-isopropylacrylamide)for Use in Protein Purification[J].Biomacromolecules,2006(4):1124-1130. |
| [16] | 吴世康.荧光探针技术在高分子科学中的应用[J].化学进展,1996(02):118. |
| [17] | Wilhelm M;Zhao C L;Wang Y C et al.Poly(styrene-ethylene oxide) block copolymer micelle formation in water:A fluorescence probe study[J].MACROMOLECULES,1991,24(5):1033. |
| [18] | Kalyanasundaram K;Thomas J K .Environmental effects on vibronic band intensities in pyrene monomer fluorescence and their application in studies of micellar systems[J].Journal of the American Chemical Society,1977,99(7):2039. |
| [19] | 高峰,任碧野,童真."标记"芘的激基缔合物荧光在水溶性高分子研究中的应用[J].高分子通报,2000(04):49-58. |
| [20] | Wang, Y;Feng, YJ;Wang, BQ;Lu, ZY .A Novel Thermoviscosifying Water-Soluble Polymer: Synthesis and Aqueous Solution Properties[J].Journal of Applied Polymer Science,2010(6):3516-3524. |
| [21] | 王毓 .热增粘智能型水溶性聚合物的制备及性能研究[D].中国科学院研究生院,2010. |
| [22] | 刘琼,吴文辉,陈颖,王建全,耿同谋,钱晓琳.荧光探针法研究疏水改性聚丙烯酰胺溶液的疏水缔合行为[J].功能高分子学报,2005(01):22-27. |
| [23] | 耿同谋.疏水缔合水溶性聚合物P（AM/NaAA/DiAC16）的合成与性能[J].化学研究与应用,2007(04):390-395. |
| [24] | McCormick C L;Hutchinson B H;Morgan S E .Studies of the behavior of acrylamide/N-(1,1-dimethyl-3-oxobutyl) acrylamide copolymers in aqueous salt solutions[J].Makromol Chem,1987,188:357. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%