阿尔茨海默症药物的开发对该疾病的治疗非常重要.利用纳米金为探针研究了13种化合物抑制Cu2+诱导的β-淀粉样蛋白聚集的能力,筛选出了10种有效的抑制剂,并获得了抑制剂抑制能力与其分子结构间的关系,利用筛选出的抑制剂实现了β淀粉样蛋白聚集过程的抑制和H2 O2产生量的减少,对阿尔茨海默症的研究具有重要意义.
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