欢迎登录材料期刊网

材料期刊网

高级检索

对等离子喷涂HA/Ti复合涂层进行模拟体液和体外细胞试验,以考察涂层的生物学性能.结果指出,涂层经模拟体液浸泡后,表面覆盖一层碳酸磷灰石(carbonate-apatite),这表明涂层具有良好的生物活性.粗糙的涂层表面易于形成碳酸磷灰石.模拟体液的浓度太小或pH值太大,均会导致碳酸磷灰石层不能在涂层表面形成.体外细胞试验显示,成骨细胞能在涂层表面紧密贴壁并正常生长,显示涂层具有优良的生物相容性.

SBF test and cell culture in vitro were carried out to evaluate the biological properties of plasma sprayed HA/Ti composite coatings. Results obtained show that the coating surfaces will be covered by carbonate-apatite layer after being immersed in SBF for 1 day, which indicate that the composite coatings possess good bioactivity. Carbonate-apatite layer is inclined to form on the rougher coating surface. Low concentration and high pH value of SBF are harmful to the formation of carbonate-apatite layer. Excellent biocompatibility of the composite coatings can be confirmed by osteoblasts attaching firmly and growing well on the coating surface.

参考文献

[1] Groot K, Wolke J G C, Jansen J A. Proc. Instn Mech. Engrs. (Part H), 1998, 212: 137-147.
[2] Kurzweg H, Heimann R B, Troczynski T. J. Mater. Sci.: Mater. In Med., 1998, 9: 9-16.
[3] 郑学斌,丁传贤( ZHENG Xue-Bin,et al.无机材料学报(Journal of Inorganic Materials),2000,15(5):897-902.
[4] Chang E, Chang W J, Wang B C, et al. J. Mater. Sci.: Mater. In Med., 1997, 8: 201-211.
[5] Kirkpatrick C J, Bittinger F, Wagner M, et al. Proc. Instn Mech. Engrs. (Part H), 1998, 212:75-84.
[6] Wen H B, Wolke J G C, Wijn J R, et al. Biomaterials, 1997, 18 (22): 1471-1478.
[7] Heimann R B, Kurzweg H, Vu T A. In: Coddet C. ed. Proceeding of the 15th international thermal spray conference (France). USA: ASM International, 1998. 999-1003.
[8] Kokubo T, Miyaki F, Kim H, et al. J. Am. Ceram. Soc., 1996, 79: 1127-1129.
[9] Kim H M, Miyaji F, Kokubo T, et al. J. Am. Ceram. Soc., 1995, 78: 2405-2411.
[10] Weng J, Liu Q, Wolke J G C, et al. Biomaterials, 1997, 18 (15): 1027-1035.
上一张 下一张
上一张 下一张
计量
  • 下载量()
  • 访问量()
文章评分
  • 您的评分:
  • 1
    0%
  • 2
    0%
  • 3
    0%
  • 4
    0%
  • 5
    0%