从整体论、系统论和复杂科学的角度论述了中药指纹图谱学体系的构成背景和核心任务.中药指纹图谱学体系具有体系科学性质,是从系统性和整体性角度研究中药(包括植物药)的物质基础和作用机制以及药代动力学规律和相关制剂技术的崭新学科.该体系以中药指纹图谱信息学为核心和桥梁,包括中药指纹图谱测试学、中药指纹图谱质控学、中药指纹图谱谱效学、中药指纹药物动力学、中药指纹药剂学和中药生物指纹图谱学.该体系的研究需采用复杂科学和体系科学的理论和方法,突破线性思维和还原分析,强调宏观和系统的有机综合,应用数学科学原理和方法来开辟中药创制的新模式.中药指纹图谱学的理论体系和方法是解析中药的主导技术和实现中药现代化的核心力量,该体系理论和技术的成熟及完善可为现代中药创制提供强有力的理论和技术支撑.中药指纹图谱学体系的最终目的是为人类和有益生物研制出疗效显著、安全、可控的现代化中药.
参考文献
| [1] | Sun G X,Luo C X,Ren P P,et al.Central South Pharmacy(孙国祥,雒翠霞,任培培,等.中南药学),2007,5(1):69 |
| [2] | Sun L X,Ren J,Wang M W,et al.Journal of Shenyang Pharmaceutical University(孙立新,任靖,王敏伟,等.沈阳药科大学学报).2005,22(3):126 |
| [3] | Luo G A,Wang Y M,Cao J,et a1.World Science and Tech-nology-Modernization of Traditional Chinese hiedieine and Materria Medica(罗国安,王义民,曹进.等.世界科学技术-中药现代化杂志),2002.4(4):5 |
| [4] | Xie P S.Traditional Chinese Drug Research ＆ Clinical Phar-maeology(谢培山.中药新药与临床药理),2001,12(3):188 |
| [5] | Liu X Y.Liu G Y,Yu J H.Tianjin Pharmacy(刘小瑜.吕圭源,俞景华.天津药学),2006,18(1):46 |
| [6] | Zheng Y B,wu J Z.Chinese ArchJves of Traditional Chinese Medicine(郑远斌,吴锦忠.中医药学刊),2004,22(4):763 |
| [7] | Xie P S.China Journal of Chinese blateria blediea(谢培山.中国中药杂志),2006,26(10):653 |
| [8] | Qiao Y J,Wang X,Bi K S,et al.Acta Pharmaeeutiea Siniea(乔延江,王玺,毕开顺,等.药学学报),1995,31(9):698 |
| [9] | Sun L X,Ning L L,Bi K S,et al.Joumal of Chinese Medici-rml Materials(孙立新,宁黎丽,毕开顺,等.中药材),2000,23(10):609 |
| [10] | Meng Q H,Liu Y S,Wang J S,et al.Chinese Traditional Patent Nedicine(孟庆华,刘永锁,王健松,等.中成药),2003,25(1):4 |
| [11] | Nie L,Cao J,Luo G A,et al.Chinese Traditional Patent Medicine(聂磊,曹进,罗国安,等.中成药),2005,27(3):249 |
| [12] | Sun GX,Ren P P.Bi Y M,et al.Chinese Joumal of (Chro-matography(孙国祥,任培培,毕雨萌,等.色谱),2007,25(4):518 |
| [13] | Sun G X,Hou Z F,Zhang C L.et;a1.Aeta Pharmaeeutiea Sinica(孙国祥,侯志飞,张春玲,等.药学学报),2007,42(1):75 |
| [14] | Sun G X,Song Y,Bi Y M,et;al.Central South Pharmacy(孙国祥,宋杨,毕雨萌,等.中南药学),2007.5(3):263 |
| [15] | Sun G X,Hou Z F,Bi Y M,et al.Acta Pharmaeeutiea Sin-ica(孙国祥,侯志飞,毕雨萌.等.药学学报),2006,41(9):857 |
| [16] | Sun G X,Yang H T,Liu W F,et al.Chinese Traditional Patent Medicine(孙国祥,杨宏涛,刘唯芬,等.中成药),2007,29(7):937 |
| [17] | Sun G X,Liu J D,Hou Z F,et al.Chinese Journal of Phar-maeeutical Analysis(孙国祥,刘金丹,侯志飞,等.药物分析杂志),2007,27(6):791 |
| [18] | Sun G X,Yu X M,Bi K S.Chinese Traditional Patent Ned-icine(孙国祥,于秀明,毕开顺.中成药),2007,29(9):1249 |
| [19] | Sun G X,ShiCY,Bi K S.Chinese Traditional Patent bled-ieine(孙国祥,时存义,毕开顺.中成药),2007,29(10):1405 |
| [20] | Sun G X,Liu X L,Jiang B,et al.Central South Pharmacy(孙国祥,刘晓丽,姜玢,等.中南药学),2007,5(4):362 |
| [21] | Sun G X,Bi Y M,Liu J D,et al.Central South Pharmacy(孙国祥,毕雨萌,刘金丹,等.中南药学),2007,5(1):79 |
| [22] | Sun G X,Mu S X,Hou Z F,et al.Chinese Traditional Pa-tent bledieine(孙国祥,慕善学,侯志飞,等.中成药),2007,29(2):161 |
| [23] | Sun G X Yang H T,Deng X Y.et al.Chinese Journal of Chromatography(孙国祥,杨宏涛,邓湘昱,等.色谱),2007,25(1):96 |
| [24] | Sun G X,Liu J D,Chert D w.Chinese Journal of Pharma-ceutieal Analysis(孙国祥,刘金丹,陈大为.药物分析杂志),2008,28:in press |
| [25] | Sun G X,Hou Z F,Song W J.Chinese Traditional Patent bledieine (孙国祥,侯志飞,宋文璟}.中成药),2007,29(11):1561 |
| [26] | Sun G X,Liu J D,zong D S,et al.Central South Pharma-cy(孙国样,刘金丹,宗东升,等.中南药学).2006,4(5):323 |
| [27] | Sun G X,Wang L,Hou Z F.Chinese Tradilional Patent Medicine(孙国样,王璐,侯志飞.中成药),2008,in press |
| [28] | Sun G X,Ren P P,Luo C X,et al.Central south pharmacy(孙国祥,任培培,雒翠霞.等.中南药学),2007,5(2):168 |
| [29] | Xie P S.Chromatographic fingerprint of traditional Chinese medicine.Beijing:People's Health Publishing House(谢培山.中药色谱指纹图谱.北京:人民卫生出版社),2004:125 |
| [30] | Hong Z Y,Luo G A,Wang M Y,et al.Chinese Phamlaceu-tical Journal(洪战英,罗国安,王义明,等.中国药学杂志),2005,40(9):649 |
| [31] | [3l]Song P,Yu J.The Medicine Magazine of China(宋萍,于军.中国医学杂志),2006,4(3):71 |
| [32] | Ning L L,Bi K S.Wang R,et al.Acta Pharmaeeutiea Sini-ca(宁黎丽,毕开顺,王瑞,等.药学学报),2000,35(2):131 |
| [33] | Huo Y S.[ND Dissertation].Shenyang:Shenyang Phar-maeeutieal University(霍艳双.[硕士学位论文].沈阳:沈阳药科大学),2005 |
| [34] | Li R,Yan Z Y,Xu T,et al.Journal of Traditional Chinese Medieine(李戎,闫智勇,徐涛,等.现代中药),2002,10:18 |
| [35] | Lu H M,Liang Y Z,Qian P.Acta Pharmaceutica Siniea(卢红梅,梁逸曾,钱频.药学学报),2005,40(12):1147 |
| [36] | Li Y J,Wang R,Che Z T.The collection of international conference in assessing TCM quality by chromatographic fingerprints(李玉娟,王瑞,车镇涛.国际色谱指纹图谱评价中药质量研讨会学术报告论文集),2001:128 |
| [37] | He F Y,Luo J Y,Liu W L.World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica(贺福元.罗杰英,刘文龙.世界科学技术-中医药现代化),2004,6(6):44 |
| [38] | Gao Q T.[PhD dissertation].Shenyang:Shenyang Phar-maeeutieal University(高秋涛.[博士学位论文].沈阳:沈阳药科大学),2005 |
| [39] | Dou Z H.Ding A W,Wang L J,et al.Chinese Traditional and Herbal Drugs(窦志华,丁安伟,王陆军,等.中草药),2007,37(8):1137 |
| [40] | Li X N,Wang Q,Zhang G H,et a1.China Journal of Traditional Chinese Medicine and Pharmacy(李小娜,王巧,张国华,等.中华中医药杂志),2006,21(10):617 |
| [41] | Wang Y L,Liang Y Z,Chen L,et al.Research and Practice on Chinese Medicines(王亚丽,粱逸曾,陈练,等.现代中药研究与实践),2004,18(B12):75 |
| [42] | Song J C,Zeng J F,Hu C Q,et al.Chinese Journal of Nat-ural Medicines(宋金春,曾俊芬,胡传芹,等.中国天然药物),2005,40(13):977 |
| [43] | Wang X J,Zhang N,Sun H,et al.Chinese Journal of Nat-ural Medicines(王喜军,张宁,孙晖,等.中国天然药物),2004,2(4):219 |
| [44] | Wei L H,Sun W Y.Journal of Shandong University of TCM(魏陆海,孙维洋.山东中医药大学学报),2006,30(4):336 |
| [45] | Xu W,Lin D H.Liu C X.Aeta Pharmaceutiea Siniea(徐雯,林东海,刘昌孝.药学学报),2005,40(9):769 |
| [46] | Ran X R,Liang Q L,Luo G A,et a1.Chinese Traditional Patent Medicine(冉小蓉,梁琼麟,罗国安,等.中成药),2005,27(4):381 |
| [47] | Wang Z P,Qiao J J,Yuan Y J.Chinese Traditional and Herbal Drugs(正志平,乔建军,元英进.中草药),2004,35(1):l |
| [48] | Xiao X H,Jin C,Zhao Z Z.China Journal of Chinese Mate-ria Mediea(肖小河,金城,赵中振.中国中药杂志),2007,34(14):1377 |
| [49] | Shang G W,Jiang Y P,Mei Q B,et al.Chinese Traditional Patent Medicine(尚刚伟,蒋永培,梅其炳,等.中成药),2002,24(3):161 |
| [50] | Liang X M,Xu Q,Zhang F F.Bulletin of the Chinese Academy of Sciences(梁鑫森,徐青,章飞芳.中国科学院院刊),2004,19(3):218 |
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