用生物矿化交替沉积法成功在CS基质膜表面构建HA涂层,并进行了表征.结果表明,HA含量随着沉积循环数增加而增加,且在4个循环后基本达到饱和,饱和含量为8.8%;随着沉积循环数增加HA由均一颗粒状转变为无规则平板状;拉伸强度由纯CS膜的68.6 MPa降低到沉积5个循环后的46.9 MPa.控制沉积数可调控HA的含量、形貌和力学强度,以满足引导组织再生术需要.
参考文献
| [1] | R.G.Caffesse,C.E.Nasjleti,E.C.Morrison,R.Sanchez,Guided tissue regeneration:comparison of bioabsorbable and non-bioabsorbable membranes.Histologic and histometric study in dogs,J Periodontal,65(6),583(1994) |
| [2] | A.Piattelli,A.Scarano,P.Russo,S.Matarasso,Evaluation of guided bone regeneration in rabbit tibia using bioresorbable membranes,Biomaterials,17(8),791(1996) |
| [3] | B.F.Paul,J.T.Malloning,H.J.Towlw,J.L.Gray,Use of a collagen barrier to enhance healing in human periodontal furcation defects,Int.J.Periodontics Restorative Dent.,12(2),122(1992) |
| [4] | D.Quteish,A.E.Dolby,The use of irradiated-crosslinked human collagen membrane in guided tissue regeneration,J.Clin.Periodontal,19,476(1992) |
| [5] | U.Yoshiya,I.Kunio,M.Takamitsu,K.Takahiro,N.Hitoshi,S.Kazuomi,R.Kazuo,Usefulness as guided bone regeneration membrane of the alginate membrane,Biomaterials,23,2027(2002) |
| [6] | P.Robert,J.Mauduit,R.M.Frank,M.Vert,Biocompatibility and resorbability of a polylactic acid membrane for periodontal guided tissue regeneration,Biomaterials,14,353(1993) |
| [7] | E.Milella,G.Barra,P.A.Ramires,G.Leo,P.Aversa,A.Romito,Poly(L-lactide) acid/alginate composite membranes for guided tissue regeneration,J.Biomed.Mater.Res.,57,248(2001) |
| [8] | S.M.Kuo,S.J.Chang,T.W.Chen,T.C.Kuan,Guided tissue regeneration for using a chitosan membrane:an experimental study in rats,J.Biomed.Mater.Res.,76A,408(2006) |
| [9] | Sundararajan V.Madihally,Howard W.T.Matthew,Porous chitoan scaffolds for tissue engineering,Biomaterials,20,1133(1999) |
| [10] | Q.L.Hu,Z.P.Fang,Y.Zhao,C.W.Xu,A new method to prepare chitosan membrane as a biomedical material,Chinese Journal of Polymer Science,19(5),467(2001) |
| [11] | Jianbiao Ma,Hongjun Wang,Binglin He,Jiatong Chen,A preliminary in vitro study on the fabrication and tissue engineering applications of a novel chitosan bilayer material as a scaffold of human neofetal dermal fibroblasts,Biomaterials,22,331(2001) |
| [12] | Qiaoling Hu,Baoqiang Li,Mang Wang,Jiacong Shen,Preparation and characterization of biodegradable chitosan/hydroxyapatite nanocomposites rods via in situ hybridization:a potential material as internal of bone fracture,Biomaterials,25,779(2004) |
| [13] | L.Illum,I.J.Gill,M.Hinchcliffe,A.N.Fisher,S.S.Davis,Chitosan as a novel nasal delivery system for vaccines,Advanced Drug Delivery Reviews,51,81(2001) |
| [14] | R.A.Muzzarelli,C.Zucchini,P.Ilari,A.Pugnaloni,M.M.Belrnonte,G.Biagini,C.Castaldini,Osteoconductive properties of methylpyrrolidinone chitosan in animal model,Biomaterials,14,925(1993) |
| [15] | F.Ali,B.S.Galen,Z.Rebecca,S.Sevda,Chitosan supports the initial attachment and spreading of osteoblasts preferentially over fibrolasts,Biomaterials,25,2075(2004) |
| [16] | SUN Qinfeng,ZHUANG Zhaoxiao,YANG Pishan,CAO Zongshun,LU Fengqi,LI Zhenyu,Experimental studies of periodontal new attachment using chitosan membrane,Journal of Shan Dong University (Heath Sciences),36(4),301(1998)(孙钦峰,庄昭霞,杨丕山,曹宗顺,卢凤琦,李振玉.壳聚糖膜促进牙周新附着的实验研究,山东大学学报(医学版),36(4),301(1998)) |
| [17] | ZHANG Yi,ZHUANG Zhaoxiao.LU Fengqi,CAO Zongshun,Biocompatibility of chitosan as membrane for periodontal guide tissue regeneration,Journal of Shan Dong University (Heath Sciences),40(2),115(2002)(张毅,庄昭霞,卢凤琦,曹宗顺,牙周引导组织再生壳聚糖膜的生物相容性研究,山东大学学报(医学版),40(2),115(2002)) |
| [18] | CHU Chengling,ZHU Jingchuan,YIN Zhongda,WANG Shidong,Advancement of hydroxyapatite(HA) biological composites,Materials Review,13(2),51(1999)(储成林,朱景川,尹钟大,王世栋,羟基磷灰石(HA)生物复合材料的研究进展,材料导报,13(2),51(1999)) |
| [19] | A.Sabokbar,R.Paney,J.Diaz,J.M.Quinn,D.W.Murray,N.A.Athanasou,Hydroxyapatite particles are capable of inducing osteoclast formation,Journal of Materials Science:Materials in Medicine,12,659(2001) |
| [20] | Huipin Yuan,K.Kurashina,J.D.de Bruijn,Yubao Li,K.de Groot,Xingdong Zhang.A preliminary study on osteoinduction of two kinds of calcium phosphate ceramics,Biomaterials,20,1799(1999) |
| [21] | Yunzhi Yang,K.H.Kim,L.O.Joo,A review on calcium phosphate coatings produced using a sputtering processan alternative to plasma spraying,Biomaterials,26,327(2005) |
| [22] | T.Tauguchi,A.Kishida,M.Akashi,Hydroxyapatite formation on/in poly(vinyl alcohol) hydromel matrices using a novel alternate soaking process,Chem.Lett.,711(1998) |
| [23] | T.Taguchi,Y.Muraoka,H.Matsuyama,A.Kishida,M.Akashi,Apatite coating on hydrophilic polymer grafted poly(ethylene) films using an alternate soaking process,Biomaterials,22,53(2001) |
| [24] | T.Furuzono,T.Taguchi,A.Kishida,M.Akashi,Y.Tamada,Preparatiom and characterization of apatite deposited on silk fabric using an alternate soaking process,J.Biomed.Mater.Res.,50,344(2000) |
| [25] | XU Shi-tong,Clinical study of immediate implantations using guided tissue regeneration,Journal of Comprehensive Stomatology,16(2),127(2000)(徐世同,引导组织再生即刻种植术的临床研究,口腔医学纵横杂志,16(2),127(2000)) |
| [26] | WAN Pen,Tachaboonyakiat,S.Takeshi,M.Akashi,Hydroxyapatite formation on/in biodegradable chitosan hydrogels by an alternate soaking process,Polymer Journal,33(2),177(2001) |
| [27] | Yu Jiyin,Xiaoyan Luo,Junfeng Cui,Changyong Wang,Ximin Guo,Kangde Yao,A study on biomineraliztion behavior of N-methylene phosphochitosan scaffolds,Macromolecular Bioscience,4,971(2004) |
| [28] | D.D.Deligianni,N.D.Katsala,P.G.Koutsoukos,Y.F.Missirlis,Effect of surface roughness of hydroxyapatite on human bone marrow cell adhesion,proliferation,differentiation and detachment strength,Biomaterials,22,87(2001) |
| [29] | I.Hiroyuki,O.Tomokazu,O.Tsutomu,K.Kawakami,Hydroxyapatite for use as an animal cell culture substratum obtained by an alternate soaking process,Biochemical Engineering Journal,20,155(2004) |
| [30] | I.Michio,H.Yuichi,M.Nakajima,H.Yagasaki,A.H.Kafrawy,Effect of hydroxyapatite content on physical properties and connective tissue reactions to a chitosan-hydroxyapatite composite membrane,J.Biomed.Mater.Res.,45,204(1999) |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%