进行 3-氨丙基膦酸(APP)在Ti-O薄膜表面的自组装并在其表面接枝明胶分子,研究了细胞相容性.结果表明,APP自组装的最佳温度为80℃,时间为4 h,自组装后水接触角降低,表面C、N元素含量提高;表面明胶在模拟体液中前4d有少量释放,之后体系稳定,稳定后表面明胶的有效密度为2.3μg/cm2.接枝改性后的Ti-O薄膜表面促进了内皮细胞的生长和增殖,提高了表面的细胞相容性.
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