在不同反应体系中,研究了固定化红酵母细胞催化对甲氧基苯乙酮不对称还原合成(S)-1-(4-甲氧基)-苯基乙醇的反应.结果表明,在含离子液体的混合反应体系和双相反应体系中,该不对称还原反应的效率得到了不同程度的提高.此外,离子液体中阴阳离子类型对该反应的影响较大,特定阴阳离子间的匹配对同定化红酵母细胞发挥最佳催化效果至关重要.
参考文献
| [1] | Hillier, MC;Marcoux, JF;Zhao, DL;Grabowski, EJJ;McKeown, AE;Tillyer, RD .Stereoselective formation of carbon-carbon bonds via S(N)2-displacement: Synthesis of substituted cycloalkyl[b]indoles[J].The Journal of Organic Chemistry,2005(21):8385-8394. |
| [2] | Hillier M C;Desrosiers J N;Marcoux J F;Grabowski E J J .[J].Organic Letters,2004,6:573. |
| [3] | Mukaiyama T;Nagata Y;Ikegai K .[J].Chemistry Letters,2005,34:1676. |
| [4] | Xue L;Zhou D J;Tang L;Ji X F Huang M Y Jiang Y Y .[J].Reactive and Functional Polymers,2004,58:117. |
| [5] | Utsukihara T;Misumi O;Kato N;Kuroiwa T;Horiuchi CA .Reduction of various ketones by red algae[J].Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry,2006(8):1179-1185. |
| [6] | Yang W;Xu JH;Xie Y;Xu Y;Zhao G;Lin GQ .Asymmetric reduction of ketones by employing Rhodotorula sp AS2.2241 and synthesis of the beta-blocker (R)-nifenalol[J].Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry,2006(12):1769-1774. |
| [7] | Homann MJ.;Vail RB.;Previte E.;Tamarez M.;Morgan B.;Dodds DR.;Zaks A. .Rapid identification of enantioselective ketone reductions using targeted microbial libraries[J].Tetrahedron,2004(3):789-797. |
| [8] | Pollard DJ;Woodley JM .Biocatalysis for pharmaceutical intermediates: the future is now.[J].Trends in biotechnology,2007(2):66-73. |
| [9] | 娄文勇 .[D].华南理工大学学报,2005. |
| [10] | Park S;Kazlauskas RJ .Biocatalysis in ionic liquids - advantages beyond green technology [Review][J].Current Opinion in Biotechnology,2003(4):432-437. |
| [11] | Welton T .[J].Chemical Reviews,1999,99:2071. |
| [12] | van Rantwijk F;Lau RM;Sheldon RA .Biocatalytic transformations in ionic liquids [Review][J].Trends in Biotechnology,2003(3):131-138. |
| [13] | Aki S N V K;Brennecke J F;Samanta A.[J].Chemical Communications,2001:413. |
| [14] | Kragl U;Eckstein M;Kaftzik N .Enzyme catalysis in ionic liquids.[J].Current Opinion in Biotechnology,2002(6):565-571. |
| [15] | Sheldon R A;Lau R M;Sorgedrager M J;van Rantwijk F Seddon K R .[J].Green Chemistry,2002,4:147. |
| [16] | 张帆,倪晔,孙志浩,郑璞,林文清,朱坡,居年丰.水/离子液体两相体系中出芽短梗霉催化 4-氯-乙酰乙酸乙酯不对称还原合成（S）-4-氯-3-羟基-丁酸乙酯[J].催化学报,2008(06):577-582. |
| [17] | Lou WY;Zong MH;Smith TJ .Use of ionic liquids to improve whole-cell biocatalytic asymmetric reduction of acetyltrimethylsilane for efficient synthesis of enantiopure (S)-1-trimethylsilylethanol[J].Green chemistry,2006(2):147-155. |
| [18] | 朱彤波,陈军,张益,杨蕴刘,焦瑞身.提高三角酵母细胞DAO表观活力的透性化研究[J].生物工程学报,2001(01):73-77. |
| [19] | 于明安,朱晓冰,祁巍,赵领,魏郁梦.CTAB透性化酵母细胞生物催化合成（S）-（+）-3-羟基丁酸乙酯[J].催化学报,2005(07):609-613. |
| [20] | 魏娜,李柏林,欧杰.细胞膜通透性调节在发酵代谢中的重要性[J].食品科技,2006(09):14-17. |
| [21] | 韦祎;张淑荣;刘春巧;张鹏 .[J].化工学报,2007,58:2352. |
| [22] | Garcia MT;Gathergood N;Scammells PJ .Biodegradable ionic liquids - Part II. Effect of the anion and toxicology[J].Green chemistry,2005(1):9-14. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%