以离子液体1-丁基-3-甲基咪唑乙酸盐([bmim]OAc)为催化剂,以芳香胺和碳酸丙烯酯为原料,一步合成了5-甲基-3-芳基噁唑烷-2-酮.系统考察了反应温度、反应时间以及催化剂用量对反应性能的影响.在优化的反应条件下,5-甲基-3-苯基噁唑烷-2-酮的收率可达99％.研究了离子液体阴阳离子结构对反应性能的影响,发现不同阳离子离子液体的催化活性顺序为1-丁基-3-甲基咪唑([bmim])＞1,2-二甲基-3-丁基咪唑([bmmim])＞1-丁基吡啶([bpy]),与其中阳离子在催化过程中提供氢键的能力一致;不同阴离子离子液体的催化活性顺序为OAc＞ C1＞ Br＞ BPh4,与其中阴离子在催化过程中接受氢键的能力一致.离子液体阴阳离子协同催化芳香胺与碳酸丙烯酯的反应.离子液体[bmim]OAc催化剂可重复使用5次,其活性未见明显下降.
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