研究了没食子酸丙酯在水溶液中分别与Fe~(3+)、Cr~(3+)、Cu~(2+)生成没食子酸丙酯-铁(PG-Fe)、没食子酸丙酯-铬(PG-Cr)、没食子酸丙酯-铜(PG-Cu)这3种金属配合物(PG-M)的反应.通过紫外光谱、核磁共振、红外光谱、质谱、元素分析、摩尔电导率和循环伏安法等测试技术对3种金属配合物进行了表征.确定3种金属配合物的分子式分别为[C_(10)H_(10)O_5]_2Fe·H_2O、[C_(10)H_(10)O_5]_3Cr·2H_2O、[C_(10)H_(10)O_5]_2Cu·2H_2O.红外光谱分析表明,中心金属原子与酚羟基发生配位,形成Ar-O-M键.电化学数据显示,PG-M的抗氧化性优于PG配体,且PG-Cu＞PG-Cr＞PG-Fe.用改进的核黄素光还原NBT法检测了3种金属配合物的模拟超氧化物歧化酶(SOD)活性.结果表明,3种金属配合物均有一定的催化歧化超氧阴离子自由基(O_2~-·)活性,均可被称作超氧化物歧化酶活性中心的模拟配合物.
The interactions of Fe~(3+) ,Cr~(3+) ,Cu~(2+) with propyl gallate(PG) in water were studied. The solid complexes of PG-Fe,PG-Cr,PG-Cu were characterized by UV-Vis,~1H NMR,IR,MS,elemental analysis,molar conductance and cyclic voltammetry. The results support the formation of the complexes with the formulae [C_(10)H_(10)O_5]_2Fe·H_2O,[C_(10)H_(10)O_5] _3Cr·2H_2O and [C_(10)H_(10)O_5] _2Cu·2H_2O for investigated metal cations. The IR spectra show that the phenol hydroxyl group was coordinated to the metal center to form the Ph-O-M bond. The electrochemical data suggest that the metal complexes were more effective antioxidants than PG ligand,and the antioxidative property follows the order:PG-Cu＞PG-Cr＞PG-Fe. The superoxide dismutase(SOD) like activity of the metal complexes was measured by means of a reduction of NBT by V_(B2). The results indicate that the three metal complexes could catalyze the disproportionation of the superoxide anion free radical (O_2~-·),and could be used as the active center model complexes of SOD.
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