采用荧光光谱、差热扫描和核磁共振法研究了不同酸度和温度下β-环糊精(β-CD)、羟丙基-β-环糊精(HP-β-CD)和磺丁醚-β-环糊精(SBE-β-CD)对氯诺昔康(LX)的包合特性.结果表明,3种环糊精与氯诺昔康均形成1∶1的包合物.以包合常数作为包合稳定性的量度,包合稳定性为SBE-β-CD>HP-β-CD>β-CD.
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