根据模拟钒卤代过氧化物酶(V-HPOs)活性中心的配位环境,设计并合成了2种新型过氧钒配合物:Na[VO(O2)2(C10H8N2)]·8H2O(1)和K3H[(VO)2 (O2)4(μ2-O)]·H2O(2),通过元素分析、红外光谱和紫外光谱对其进行了表征,并通过X射线单晶衍射方法确定了其结构.配合物1晶体属于三斜晶系,空间群:P-1,a=0.7213(2) nm,6=1.1269(4) nm,c=1.3728 (4) nm,α=68.349(4)°,β=89.178(4)°,γ=88.050(4)°,V=1.0365(6) nm3.配合物2的晶体属于单斜晶系,空间群:P21/c,a=0.67047 (12) nm,6 =0.99503(18) nm,c=1.5817(3) nm,α=γ=90°,β=93.739(2)°,V=1.0530(3) nm3.配合物1和2分别是五角双锥和八面体配位构型.通过催化溴化反应活性研究发现,2种配合物均可作为潜在的钒卤代过氧化物酶模拟物.
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