欢迎登录材料期刊网

材料期刊网

高级检索

通过铑催化不对称催化氢化的方法,实现了2-苯基-2-丙烯醇的不对称催化氢化,对一系列单齿及双齿磷配体进行了筛选,在温和的条件下,以较高对映体选择性的合成了手性2-苯基丙醇,最高获得了70%的ee值.

参考文献

[1] Abate A;Brenna E;Fuganti C.Chirality and Fragrance Chemistry:Stereoisomers of the Commercial Chiral Odorants Muguesia and Pamplefleur[J].Journal of Organic Chemistry,200570(04):1281-1290.
[2] Serra S.Lipase-mediated Resolution of Substituted 2-Aryl-propanols:Application to the Enantioselective Synthesis of Phenolic Sesquiterpenes[J].Tetrahedron:Asymmetry,201122(06):619-628.
[3] Wipf P;Ribe S.Water/MAO Acceleration of the Zirconocene-Catalyzed Asymmetric Methylalumination of r-Olefins[J].Organic Letters,20002(12):1713-1716.
[4] Deerenberg S;Kamer P C J;van Leeuwen P W N M.New Chiral Phosphine-Phosphite Ligands in the Enantioselective Rhodium-Catalyzed Hydroformylation of Styrene[J].ORGANOMETALLICS,200019(11):2065-2072.
[5] de Vries J G;Elsevier C J .The Handbook of Homogeneous Hydrogenation[D].Wiley-VCH,Weinheim,Germany,2007.
[6] Coil M;Pàrnies O;Diégueza M.A Modular Furanoside Thioether-Phosphite/Phosphinite/Phosphine Ligand Library for Asymmetric Iridium-Catalyzed Hydrogenation of Minimally Functionalized Olefins:Scope and Limitations[J].Advanced Synthesis and Catalysis,2013355(01):143-160.
[7] Mazuela J;Norrby P O;Andersson P G.Pyranoside Phosphite-Oxazoline Ligands for the Highly Versatile and Enantioselective Ir-Catalyzed Hydrogenation of Minimally Functionalized Olefins.A Combined Theoretical and Experimental Study[J].Journal of the American Chemical Society,2011133(34):13634-13645.
[8] K(a)llstrtr(o)m K;Hedberg C;Brandt P.Rationally Designed Ligands for Asymmetric Iridium-Catalyzed Hydrogenation of Olefins[J].Journal of the American Chemical Society,2004126(44):14308-14309.
[9] Zeng Q H;Hu X P;Duan Z C.Unsymmetrical Ferrocenylethylamine-Derived Monophosphoramidites:Highly Efficient Chiral Ligands for Rh-Catalyzed Enantioselective Hydrogenation of Enamides and α-Dehydroamino Acid Derivatives[J].Journal of Organic Chemistry,200671(01):393-396.
[10] Huang J D;Hu X P;Duan Z C.Readily Available Phosphine-Phosphoramidite Ligands for Highly Efficient Rh-Catalyzed Enantioselective Hydrogenations[J].Org Leu,20068(19):4367-4370.
[11] Hu X P;Zheng Z.Unsymmetrical Hybrid Ferrocene-Based Phosphine-Phosphoramidites:A New Class of Practical Ligands for Rh-Catalyzed Asymmetric Hydrogenation[J].Organic Letters,20046(20):3585-3588.
[12] Duboudin J G;Jousseaume B;Saux A.Reactifs de Grignard Vinyliques Fonctionnels:Ⅰ.Reactivite des Organomagnesiens vis-a-vis d'alcools Acetyleniques en Presence d'halogenures Cuivreux[J].Journal of Organometallic Chemistry,1979168(01):1-11.
上一张 下一张
上一张 下一张
计量
  • 下载量()
  • 访问量()
文章评分
  • 您的评分:
  • 1
    0%
  • 2
    0%
  • 3
    0%
  • 4
    0%
  • 5
    0%