毛细管电色谱联用技术的研究进展

色谱 , 2010, 28(3): 273-283. doi: 10.3724/SP.J.1123.2010.00273

毛细管电色谱联用技术的研究进展

林子俺 ^1, , 庞纪磊 ^2, , 黄慧 ^3, , 张兰 ^4, , 陈国南 ^5,

1.食品安全分析与检测技术教育部重点实验室,福州大学化学化工学院,福建,福州,350002

2.食品安全分析与检测技术教育部重点实验室,福州大学化学化工学院,福建,福州,350002

3.食品安全分析与检测技术教育部重点实验室,福州大学化学化工学院,福建,福州,350002

4.食品安全分析与检测技术教育部重点实验室,福州大学化学化工学院,福建,福州,350002

5.食品安全分析与检测技术教育部重点实验室,福州大学化学化工学院,福建,福州,350002

基金项目: 福州大学科研启动基金(0460022233)

关键词：毛细管电色谱 , 联用技术 , 接口 , 检测技术 , 应用

Recent advances in capillary electrochromatography and its coupling techniques

Keywords： capillary electrochromatography (CEC) , coupling techniques , interface , detection techniques , application

毛细管电色谱(CEC)作为一种新型微柱分离技术,具有高效、高选择性、高分辨率和快速分离等特点.由于CEC进样体积通常为纳升级,所以对检测系统的高灵敏检测提出了很高的要求.当前,发展CEC与各种高灵敏检测器的联用已成为CEC研究中最活跃的方向之一.本文简要介绍了CEC研究的发展历程,系统综述了CEC与各类检测器联用技术及其在复杂样品分离分析中应用的最新进展,并对CEC联用技术的前景进行了展望.引用文献141篇.

As a novel micro-separation technique,capillary electrochromatography (CEC) has the merits of high efficiency,high selectivity,high resolution and rapid analysis.However,the small-volume injection manipulated in capillary dimensions poses a great challenge for detectors in achieving high sensitivity.Currently,one of the major researches into CEC involves the development of some sensitive detection modes.The general introduction,which includes the historical perspectives and the principles of CEC,is briefly described.The recent advances about CEC coupled with various detectors and its applications in the separation of complex samples are summarized.A total of 141 references are reviewed.

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