纳米粒子因其具有较大的比表面积和良好的生物相容性等特点,已广泛应用于分离科学领域.纳米粒子毛细管电泳/微流控芯片技术是纳米材料技术与毛细管电泳/微流控芯片技术相结合的产物.纳米粒子可以被吸附或键合到毛细管壁作为固定相与被分析物发生相互作用；也可以作为假固定相参与样品在柱内的分配和保留,从而提高柱效,改善分离.手性是自然界的本质属性之一,开发新的快速、高效、灵敏的手性分离分析方法对于对映体的立体选择性合成、药理研究、手性纯度检测和环境检测都具有重要的意义.本文主要综述了近些年来几种不同类型纳米粒子(聚合物纳米粒子、磁性纳米粒子、金纳米粒子、碳纳米管和其他类型纳米粒子)用于毛细管电泳/微流控芯片进行手性分离的现状,并对该领域今后的发展进行了展望.
参考文献
| [1] | Goldstein A N,Echer C M,Alivisatos A P.Science,1992,256(5062):1425 |
| [2] | Li H,Yan X H,Ding G S,et al.Journal of InstrumentalAnalysis(李慧,闫新焕,丁国生,等.分析测试学报),2010,29(6):638 |
| [3] | Natishan T K.J Liq Chromatogr Related Technol,2005,28(7/8):1115 |
| [4] | Dittrich P S,Manz A.Nat Reviews Drug Disc,2006,5 (3):210 |
| [5] | Erickson D,Li D Q.Anal Chim Acta,2004,507(1):11 |
| [6] | Guihen E,Glennon J D.Anal Letters,2003,36(15):3309 |
| [7] | Nilsson C,Birnbaum S,Nilsson S.J Chromatogr A,2007,1168(1/2):212 |
| [8] | Amini A.Electrophoresis,2001,22(15):3107 |
| [9] | Ward T J,FarrisⅢ A B.J Chromatogr A,2001,906(1/2):73 |
| [10] | Gubitz G,Schmid M G.Biopharm Drug Disp,2001,22(7/8):291 |
| [11] | Bos R,Woerdenbag H J,Pras N.J Chromatogr A,2002,967(1):131 |
| [12] | Schweitz L,Spegel P,Nilsson S.Analyst,2000,125(11):1899 |
| [13] | Wallingford R A,Ewing A G.Adv Chromatogr,1989,29:1 |
| [14] | Na N,Hu Y P,Ouyang J,et al.Anal Chim Acta,2004,527(2):139 |
| [15] | Xu W L,Cheng Z P,Zhang L F,et al.J Poly Sci Part A:Poly Chem,2010,48(6):1324 |
| [16] | Paik P,Gedanken A,Mastai Y.J Mater Chem,2010,20(20):4085 |
| [17] | Chen J L,Hsieh K H.Electrophoresis,2011,32 (3/4):398 |
| [18] | Spegel P,Schweitz L,Nilsson S.Electrophoresis,2001,22(17):3833 |
| [19] | Spegel P,Schweitz L,Nilsson S.Anal Chem,2003,75(23):6608 |
| [20] | de Boer T,Mol R,Zeeuw R A D,et al.Electrophoresis,2002,23(9):1296 |
| [21] | Priego-Capote F,Ye L,Shakil S,et al.Anal Chem,2008,80(8):2881 |
| [22] | Lise-Marie L,Don H,Sun S H. Curr Top Med Chem,2010,10(12):1184 |
| [23] | Mini N,Sutanjay S,Rasika T.J Nanosci Nanotechnol,2008,8(7):3247 |
| [24] | Daisuke K,Shogo T,Yoko I.Int J Mol Sci,2011,12(6):3705 |
| [25] | Magda L,Carlos R.Puerto Rico Health Sci J,2009,28(3):227 |
| [26] | Zhao C,Liu T,Gao J N.MINI-REV MED CHEM,2010,10(3):194 |
| [27] | Choi H J,Hyun M H.Chem Commun,2009,10(42):6454 |
| [28] | Ghosh S,Badruddoza A Z M,Uddin M S,et al.J Colloid Interf Sci,2011,354(2):483 |
| [29] | Qu P,Lei J P,Zhang L,et al.J Chromatogr A,2010,1217 (39):6115 |
| [30] | Neiman B,Grushka E,Lev O.Anal Chem,2001,73(21):5220 |
| [31] | Sardar R,Funston A M,Mulvaney P.Langmuir,2009,25(24):13840 |
| [32] | LiuF K,Wei G T,Cheng F C.Journal of the Chinese Chemical Society,2003,50 (4):931 |
| [33] | Shukla N,Bartel M A,Gellman A J.J Am Chem Soc,2010,132(25):8575 |
| [34] | Li H F,Zeng H L,Chen Z F,et al.Electrophoresis,2009,30(6):1022 |
| [35] | Yang L,Chen C J,Liu X,et al.Electrophoresis,2010,31(10):1697 |
| [36] | Li M,Liu X,Jiang F Y,et al.J Chromatogr A,2011,1218(23):3725 |
| [37] | Iijima S.Nature,1991,354(7):56 |
| [38] | Na N,Hu Y P,Ouyang J,et al.Talanta,2006,69(4):866 |
| [39] | Suarez B,Simonet B M,Cardenas S,et al.Electrophoresis,2007,28(11):1714 |
| [40] | Moliner-Martinez Y,Cardenas S,Valcarcel M.Electrophoresis,2007,28(15):2573 |
| [41] | Weng X X,Bi H Y,Liu B H,et al.Electrophoresis,2006,27(15):3129 |
| [42] | Wu C X,Wang C,Wang Z.Chinese Journal of Chromatography (武春霞,王春,王志.色谱),2011,29(1):6 |
| [43] | ChoiS H,Noh H J,Lee K P.Bull Korean Chem Soc,2005,26(10):1549 |
| [44] | Guo B J,Yang Y,Su P.Chemical Research in Chinese Universities (郭宝晶,杨屹,苏萍.高等学校化学学报),2007,28(7):1267 |
| [45] | Dong X L,Wu R A,Dong J,et al.Electrophoresis,2008,28(15):2606 |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%