近年来混合模式色谱以其独特的分离特性受到人们越来越多的关注.混合模式色谱的种类主要集中在反相/离子交换混合模式色谱(reversed-phase/ion-exchange mixed-mode chromatography,RPLC/IEX),亲水作用/离子交换混合模式色谱(hydrophilic interaction/ion-exchange mixed-mode chromatography,HILIC/IEX),反相/亲水作用混合模式色谱(reversed-phase/hydrophilic interaction mixed-mode chromatography,RPLC/HILIC)等混合模式.两种或多种机理混合使用,往往在分离选择性和色谱峰形等方面能得到不同于单一模式操作所得到的效果,分离选择性以及色谱峰形等都能得到极大的改善与提高,这使得混合模式色谱渐渐进入研究者们的视野.混合模式色谱的研究多数集中在色谱填料的设计.混合模式色谱填料的应用主要针对生物样品的分离分析.该文综述了近年来混合模式色谱的研究及其应用进展,并展望了混合模式色谱的发展.
参考文献
| [1] | Rafferty J L,Zhang L,Siepmann J I,et al.Anal Chem,2007,79(17):6551 |
| [2] | Qiu H D,Liang X J,Sun M,et al.Anal Bioanal Chem,2011,399(10):3307 |
| [3] | Miyabe K.J Sep Sci,2009,32(5/6):757 |
| [4] | McCalley D V.J Chromatogr A,2007,1171(1/2):46 |
| [5] | Francois I,Sandra K,Sandra P.Anal Chim Acta,2009,641(1/2):14 |
| [6] | Alpert A J.J Chromatogr,1990,499:177 |
| [7] | Fu Q,Liang T,Zhang X L,et al.Carbohydr Res,2010,345(18):2690 |
| [8] | Shen A J,Guo Z M,Cai X M,et al.J ChromatogrA,2012,1228:175 |
| [9] | Shen A J,Guo Z M,Yu L,et al.Chem Commun,2011,47(15):4550 |
| [10] | Gama M R,Silva R G D,Collins C H,et al.Trac-Trends Anal Chem,2012,37:48 |
| [11] | Guo H Y,Liu R H,Yang J J,et al.JChromatogr A,2012,1223:47 |
| [12] | Liu Y J,Du Q,Yang B C,et al.Analyst,2012,137(7):1624 |
| [13] | West C,Khater S,Lesellier E.J Chromatogr A,2012,1250:182 |
| [14] | Yang J,Dong J B,Ye Z D,et al.Acta Chim Sinica,2012,70(16):1725 |
| [15] | Zhang F,Li Y,Guo Z,et al.Talanta,2011,85(1):112 |
| [16] | Gaur S.J Chromatogr A,1996,733(1/2):57 |
| [17] | Weiss J,Jensen D.Anal Bioanal Chem,2003,375 (1):81 |
| [18] | Chang S P,Wang F Q,Gong B L.Chin J Chem,2011,29(4):793 |
| [19] | Hao J X,Wang F Q,Dai X J,et al.Talanta,2011,85(1):482 |
| [20] | Davies N H,Euerby M R,McCalley D V.J Chromatogr A,2007,1138(1/2):65 |
| [21] | McLaughlin L W.Chem Rev,1989,89(2):309 |
| [22] | Yang Y,Geng X D.J Chromatogr A,2011,1218(49):8813 |
| [23] | Geng X D.Chinese Journal of Chromatography (耿信笃.色谱),2012,30(1):1 |
| [24] | Mant C T,Hodges R S.J Sep Sci,2008,31(15):2754 |
| [25] | Stevenson P G,Fairchild J N,Guiochon G.J Chromatogr A,2011,1218(14):1822 |
| [26] | Wu J Y,Bicker W G,Lindner W G.J Sep Sci,2008,31(9):1492 |
| [27] | Lammerhofer M,Nogueira R,Lindner W.Anal Bioanal Chem,2011,400(8):2517 |
| [28] | Dong J,Ou J J,Dong X L,et al.J Sep Sci,2007,30(17):2986 |
| [29] | Lin H,Ou J J,Zhang Z B,et al.Anal Chem,2012,84(6):2721 |
| [30] | Borges E M,Euerby M R,Collins C H.Anal Bioanal Chem,2012,402(6):2043 |
| [31] | Alpert A J.Anal Chem,2008,80(1):62 |
| [32] | Dong X F,Shen A J,Guo Z M,et al.Carbohydr Res,2012,361:195 |
| [33] | Guo Z M,Jin Y,Liang T,et al.J Chromatogr A,2009,1216(2):257 |
| [34] | Nogueira R,Lubda D,Leitner A,et al.J Sep Sci,2006,29(7):966 |
| [35] | Guo Z M,Wang C R,Liang T,et al.J Chromatogr A,2010,1217(27):4555 |
| [36] | Cai X M,Guo Z M,Xue X Y,et al.J Chromatogr A,2012,1228:242 |
| [37] | Wei J,Guo Z M,Zhang P J,et al.J ChromatogrA,2012,1246:129 |
| [38] | Li X L,Guo Z M,Sheng Q Y,et al.Analyst,2012,137(12):2774 |
| [39] | Zhu B Y,Mant C T,Hodges R S.J Chromatogr,1991,548(1/2):13 |
| [40] | Zhu B Y,Mant C T,Hodges R S.J Chromatogr,1992,594(1/2):75 |
| [41] | Mant C T,Kondejewski L H,Hodges R S.J Chromatogr A,1998,816(1):79 |
| [42] | Mant C T,Litowski J R,Hodges R S.J Chromatogr A,1998,816(1):65 |
| [43] | Litowski J R,Semchuk P D,Mant C T,et al.J Peptide Res,1999,54(1):1 |
| [44] | Jiang W,Fischer G,Girmay Y,et al.J Chromatogr A,2006,1127(1/2):82 |
| [45] | Liu X D,Pohl C.J Chromatogr A,2008,1191(1/2):83 |
| [46] | Liu X D,Pohl C A.J Sep Sci,2010,33(6/7):779 |
| [47] | Liu X D,Pohl C,Woodruff A,et al.J Chromatogr A,2011,1218(22):3407 |
| [48] | Liu X D,Pohl C A.J Chromatogr A,2012,1232:190 |
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