以二乙酸碘苯(PIDA,2)为催化剂,分别由3,4-二甲氧基-α-(3,4-二甲氧苯基)-肉桂酸(5a)和(Z-2-(3,4-二甲氧苯基)-3-(3,4-二甲氧苯基)-丙烯腈(5b)为原料,合成了相应的2,3,6,7-四甲氧基-9-羧基菲(6a)和2,3,6,7-四甲氧基-9-氰基菲(6b),经1H NMR测试技术表征为关环产物,产率分别为65.83%和64.76%.
参考文献
| [1] | Gao Wenli,Lam Wing,Zhong Sanbao,et al.Cancer Res[J],2004,64:678 |
| [2] | ZHEN Yue-Ying(甄月英),HUANG Xue-Shi(黄学石),YU De-Quan(于德泉),YU Shi-Shan(庚石山).Acta Botanica Sin(植物学报)[J],2002,44(3):349 |
| [3] | Li Zaiguo,Jin Zhong,Huang Runqiu.Synthesis[J],2001,16:2 365 |
| [4] | Andris J Liepa,Roger E Summons.J Chem Comm[J],1977:826 |
| [5] | John E Cragg,Richard B Herbbert.J Chem Soc[J],1982:2 487 |
| [6] | Thomas F Buckley Ⅲ,Henry Rapoport.J Org Chem[J],1983,48(23):4 222 |
| [7] | Hideo Iida,Yohya Watanabe,Masao Tanaka,et al.J Org Chem[J],1984,49:2 412 |
| [8] | Keinan E,Mazur Y.J Org Chem[J],1978,43:1 020 |
| [9] | Hirofumi Tohma,Hironori Morioka,Shinobu Takizawa,et al.Tetrahedron[J],2001,57:345 |
| [10] | Pausacker K H.J Chem Synth[J],1953:107 |
| [11] | Russel J H,Hunziker H.Tetrahedron Lett[J],1969:4 035 |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%