噻吩并[2,3-b]吡啶化合物是一类重要的具有广泛生物活性的稠杂环,它们在杀菌、消炎、抗肿瘤和癌症等方面有很好的疗效,可以用作镇静剂及治疗高血压,哮喘病,糖尿病,溃疡病和神经性疾病的药物. 除在农药,医药上的用途外,还可用作染料,缓蚀剂等. 该类化合物在结构上类似于喹啉类稠杂环,其合成方法从反应物来区分,可分为以下3种情形:(1)以吡啶环为母环;(2)以噻吩环为母环;(3)不饱和硫酮化合物缩合. 综述了该类化合物的合成进展及应用情况.
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