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采用凝胶成型法制备用作骨移植和药物传递的多孔羟基磷灰石(HA)生物医用陶瓷,通过改变工艺参数制得了孔隙率和孔径可控、内部连通的三维网状开孔结构的HA,对其孔隙率、孔径及生物相容性进行了分析.结果表明:通过改变循环浸渍次数可以控制调节孔隙率在45%~92%之间;通过改变母体模板和浆料涂层的厚度可以控制孔径;制得的HA具有良好的生物相容性,具有这种特点的孔洞结构有利于骨细胞的生长.

参考文献

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