欢迎登录材料期刊网

材料期刊网

高级检索

羟基磷灰石具有良好的生物相容性、骨传导性与骨诱导性,因此被广泛应用于人工骨的制造,但因其强度和韧性较低,使其使用范围受到限制,如何提高其性能便成了研究的热点,本文综述了HAP人工骨的进展情况,并指出了其可能的发展方向.

参考文献

[1] 钱文伟,林进,邱贵兴.人工骨替代物研究进展[J].医学研究通讯,2001(04):40-43.
[2] Joschek S.;Krotz R.;Gopferich A.;Nies B. .Chemical and physicochemical characterization of porous hydroxyapatite ceramics made of natural bone[J].Biomaterials,2000(16):1645-1658.
[3] Dominic Walsh;Stephen Mann .Chemical Synthesis of Microskeletal Calcium Phosphate in Bicontinuous Microemulsions[J].Chemistry of Materials,1996(8):1944-1953.
[4] Klein C;de Groot K;Chen W et al.Osseous substance formation induced in porous calcium phosphate ceramics in soft tissues[J].Biomaterials,1994,15(01):31-34.
[5] Ozgur Engin N;Cuneyt Tas A .Manufacture of Macroporous Calcium Hydroxyapatite Bioceramics[J].Journal of the European Ceramic Society,1999,19(13-14):2369-2572.
[6] Oreffo RO;Driessens FC;Planell JA;Triffitt JT .Growth and differentiation of human bone marrow osteoprogenitors on novel calcium phosphate cements.[J].Biomaterials,1998(20):1845-1854.
[7] Khairoun I.;Driessens FCM.;Planell JA.;Boltong MG. .EFFECT OF CALCIUM CARBONATE ON THE COMPLIANCE OF AN APATITIC CALCIUM PHOSPHATE BONE CEMENT[J].Biomaterials,1997(23):1535-1539.
[8] Okazaki M;Miake Y;Tohda H;Yanagisawa T;Matsumoto T;Takahashi J .Functionally graded fluoridated apatites.[J].Biomaterials,1999(15):1421-1426.
[9] Okazaki M;Miake Y;Tohda H;Yanagisawa T;Takahashi J .Fluoridated apatite synthesized using a multi-step fluoride supply system.[J].Biomaterials,1999(14):1303-1307.
[10] Miyazaki K;Horibe T;Antouncci J M et al.Polymeric calcium phosphate cements: setting reaction modifiers[J].Dental Materials,1993,9(01):45-50.
[11] Christoffersen J;Christoffersen M R;Kolthoff N et al.Effects of strontium ions on growth and dissolution of hydroxyapatite and on bone material detection[J].Bone,1997,20(01):47-54.
[12] Miyazaki K;Horibe T;Antonucci J M et al.Polymeric calcium phosphate cements: analysis of reaction preducts and properties[J].Dental Materials,1993,9(01):41-45.
[13] Ignjatovic N;Tomic S;Dakic M;Miljkovic M;Plavsic M;Uskokovic D .Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials.[J].Biomaterials,1999(9):809-816.
[14] Lu L;Mikos A .The importance of new processing techniques in tissue engineering[J].Materials Research Bulletin,1996,21(11):28-32.
[15] Giles J A;Carnes D L;Windeler A S .Development of an vitro culture system for the study of osteoclast activity and function[J].Journal of Endodontics,1994,20(07):327-331.
[16] Bruijn J D;Bovell Y P;Davies J E et al.Osteoclastic resorption of calcium phosphates is potentiated in postosteigenic culture conditions[J].Journal of Biomedical Materials Research,1994,28(01):105-112.
[17] Miyamoto Y;Ishikawa K;Takechi M;Toh T;Yuasa T;Nagayama M;Suzuki K .Basic properties of calcium phosphate cement containing atelocollagen in its liquid or powder phases.[J].Biomaterials,1998(7/9):707-715.
[18] Asahina I;Watanabe;Mskurai N et al.Repair of bone defect in remate mandible using a bone morphogenitic protein- hydroxyapatite - collagen composite[J].Journal of Medical and Dental Sciences,1997,44(03):63-70.
[19] Kamegai A;Shimamurs N;Naitou K et al.Bone formation under the influence of bone morphogenetic protein/self - setting apatite cement composite as a delvery system[J].Biomedical Materials & Engineering,1994,4(04):291-307.
[20] Meraw SJ;Reeve CM;Lohse CM;Sioussat TM .Treatment of peri-implant defects with combination growth factor cement.[J].Journal of Periodontology,2000(1):8-13.
[21] 李世普.生物医用材料导论[M].武汉:武汉工业大学出版社,2000
[22] Seisuke K .Application of hydroxyapatite - sol as drug carrier[J].Biomedical Materials & Engineering,1994,4(04):283-290.
[23] Fu S Y;Zhu B L;Lung C W.On the pull - out of fibers with fractal tree structure and the interface of strength and fracture toughness of composites[J].Smart Materials and Structures,1992(04):180-185.
[24] Alper J .Boning up: newly isolated proteins heal bad breaks[J].Science,1994,263(5145):324-325.
上一张 下一张
上一张 下一张
计量
  • 下载量()
  • 访问量()
文章评分
  • 您的评分:
  • 1
    0%
  • 2
    0%
  • 3
    0%
  • 4
    0%
  • 5
    0%