在玻璃基生物骨水泥中掺加不同含量及粒径的颗粒状β-磷酸三钙(β-TCP),制得复合玻璃基骨水泥,在生理模拟液(SBF)中浸泡,并在不同时间取出对其微观结构和力学强度进行分析.结果表明:颗粒状β-TCP的加入有利于促进骨水泥中羟基磷灰石(HAP)的生成,由于β-TCP的降解,骨水泥的气孔率提高,力学强度下降;并且加入的颗粒状β-TCP的含量及粒度对骨水泥的强度有明显的影响.本实验在加入合适的颗粒状β-TCP下得到了一个相对较好的配比方案,使试样的气孔率和力学强度均达到较好的水平.
参考文献
| [1] | Shinzato S;Kobayashi M;Mousa WF;Kamimura M;Neo M;Kitamura Y;Kokubo T;Nakamura T .Bioactive polymethyl methacrylate-based bone cement: comparison of glass beads, apatite- and wollastonite-containing glass-ceramic, and hydroxyapatite fillers on mechanical and biological properties.[J].Journal of biomedical materials research, Part B. Applied biomaterials,2000(2):258-272. |
| [2] | Larry L. Hench .Bioceramics[J].Journal of the American Ceramic Society,1998(7):1705-1728. |
| [3] | Sous M;Bareille R;Rouais F;Clement D;Amedee J;Dupuy B;Baquey Ch .Cellular biocompatibility and resistance to compression of macroporous beta-tricalcium phosphate ceramics.[J].Biomaterials,1998(23):2147-2153. |
| [4] | 周萘,黄文,张娟,姚维芳.玻璃基生物水泥的结构研究[J].玻璃与搪瓷,2001(03):24-26,19. |
| [5] | 李世普,冯凌云,贾莉.β-Ca3（PO4）2粉末的制备及其有关性能[J].武汉工业大学学报,1995(04):146-148. |
| [6] | Kokubo T;Kushitani H;Sakka S et al.Solution able to reproduce in vivo surface-structure changes in bioactive glass-ceramic AW[J].Journal of Biomedical Materials Research,1990,24:721-734. |
| [7] | Li P J;Ohtsuki C;Kokubo T et al.Apatite formation induced by silica gel in a simulated body fluid[J].Journal of the American Chemical Society,1992,75(08):2094-2097. |
| [8] | De Aza P;Cuitianf;Merlos A et al.Bioceramics-simulated body fluid interfaces:pH and its influence of hydrowyapatite formation[J].Journal of Materials Science:Materials in Medicine,1996,7(07):399-402. |
| [9] | 付强,周萘,黄文旵,王德平.玻璃基骨水泥生物活性的研究[J].同济大学学报(自然科学版),2004(09):1178-1182. |
| [10] | LeGeros R Z .Biodergradation and bioresorption of calcium ceramics[J].Clinical Materials,1993,14:65-88. |
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