欢迎登录材料期刊网

材料期刊网

高级检索

将纳米Fe3O4按与透钙磷石骨水泥基质质量比为1∶20、1∶10及1∶5的比例加入,研究对其性能的影响.结果表明,随Fe3O4掺入增多,由于理化结构改变,骨水泥固化时间被延长至约9~27min;固化放热明显降低;可注射性和抗压强度先上升后下降,掺入比为1∶10时,可注射性(可注射系数约89%)及抗压强度(约45MPa)最优,显著高于掺杂前;在1.59×106A/m磁场下,材料饱和磁化强度从0.49A·m2/kg增加到5.51A·m2/kg,矫顽力从233.23A/m增加到707.64A/m;降解速度减缓明显,当掺入比达1∶5时,材料28d浸泡失重率由未掺杂时的约14.9%下降到约7.5%.

参考文献

[1] Matsumine A;Takegami K;Asanuma K;Matsubara T;Nakamura T;Uchida A;Sudo A .A novel hyperthermia treatment for bone metastases using magnetic materials.[J].International journal of clinical oncology,2011(2):101-108.
[2] 邹琴,张利,左奕,王华楠,李玉宝,李小玉.载黄芪多糖骨水泥的理化性能及体外细胞相容性研究[J].功能材料,2008(09):1515-1518,1521.
[3] Bock N;Riminucci A;Dionigi C;Russo A;Tampieri A;Landi E;Goranov VA;Marcacci M;Dediu V .A novel route in bone tissue engineering: magnetic biomimetic scaffolds.[J].Acta biomaterialia,2010(3):786-796.
[4] Takegami K;Sano T;Wakabayashi H;Sonoda J;Yamazaki T;Morita S;Shibuya T;Uchida A .New ferromagnetic bone cement for local hyperthermia.[J].Journal of biomedical materials research, Part B. Applied biomaterials,1998(2):210-214.
[5] Kawashita M;Kawamura K;Li Z .PMMA-based bone cements containing magnetite particles for the hyperthermia of cancer.[J].Acta biomaterialia,2010(8):3187-3192.
[6] Ana Portela;Mario Vasconcelos;Rogerio Branco;Fatima Gartner;Miguel Faria;Jose Cavalheiro .An in vitro and in vivo investigation of the biological behavior of a ferrimagnetic cement for highly focalized thermotherapy[J].Journal of Materials Science. Materials in Medicine,2010(8):2413-2423.
[7] Tamimi,F.;Sheikh,Z.;Barralet,J. .Dicalcium phosphate cements: Brushite and monetite[J].Acta biomaterialia,2012(2):474-487.
[8] 周大利,郑昌琼,尹光福,刘丹平,胡蕴玉.高性能多孔β-磷酸三钙生物陶瓷制备新工艺研究[J].生物医学工程学杂志,1999(Z1):52-55.
[9] 秦润华,姜炜,刘宏英,李凤生.Fe3O4纳米粒子的制备与超顺磁性[J].功能材料,2007(06):902-903,907.
[10] Han Bing;Ma Pengwei;Zhang Lili et al.β-TCP/MCPMbased premixed calcium phosphate cements[J].Acta Biomaterial,2009,5(08):3165-3177.
[11] Huan Zhiguang;Chang Jiang .Novel bioactive composite bone cements based on the β-tricalcium phosphate-monocalcium phosphate monohydrate composite cement system[J].Acta Biomaterial,2009,5(04):1253-1264.
[12] Bohner M;Gbureck U .Thermal reactions of brushite cements.[J].Journal of biomedical materials research, Part B. Applied biomaterials,2008(2):375-385.
[13] Cama G;Barberis F;Botter R .Preparation and properties of macroporous brushite bone cements.[J].Acta biomaterialia,2009(6):2161-2168.
[14] Kun Y;Huabei P;Yuhua W et al.Reexamination of characteristic FT-IR spectrum of secondary layer in bilayer oleic acid-coated Fe304 nanoparticles[J].Applied Surface Science,2010,25(10):3093-3097.
[15] Alkhraisat MH;Rueda C;Marino FT .The effect of hyaluronic acid on brushite cement cohesion.[J].Acta biomaterialia,2009(8):3150-3156.
[16] 宋志国,周大利,尹光福,张昭,郑昌琼.含盐酸四环素α-TCP骨水泥的理化性能[J].功能材料,2004(01):111-113.
[17] Wu,F;Wei,J;Guo,H;Chen,F;Hong,H;Liu,C .Self-setting bioactive calcium-magnesium phosphate cement with high strength and degradability for bone regeneration.[J].Acta Biomaterialia,2008(6):1873-1884.
[18] Vlad MD;Sindilar EV;Marinoso M .Osteogenic biphasic calcium sulphate dihydrate/iron-modified alpha-tricalcium phosphate bone cement for spinal applications: in vivo study.[J].Acta biomaterialia,2010(2):607-616.
[19] Shah, SA;Hashmi, MU;Alam, S;Shamim, A .Magnetic and bioactivity evaluation of ferrimagnetic ZnFe2O4 containing glass ceramics for the hyperthermia treatment of cancer[J].Journal of Magnetism and Magnetic Materials,2010(3):375-381.
[20] L. L. LAO;R. V. RAMANUJAN .Magnetic and hydrogel composite materials for hyperthermia applications[J].Journal of Materials Science. Materials in Medicine,2004(10):1061-1064.
[21] Luo Y R.Comprehensive handbook of chemical bond energies[M].Boca Raton:crc Press,2007:588-809.
上一张 下一张
上一张 下一张
计量
  • 下载量()
  • 访问量()
文章评分
  • 您的评分:
  • 1
    0%
  • 2
    0%
  • 3
    0%
  • 4
    0%
  • 5
    0%