利用生物复合法制备细菌纤维素/无纺布复合材料(BC/N),并对其结构、含水率、失水率、力学性能进行测试,结合体外细胞培养对材料进行生物安全性研究,并通过原位复合法制备载Ag的BC/N材料.结果发现,细菌纤维素(BC)与无纺布(Non)实现良好的复合,复合材料的含水率从410％提升到1 018％,失水率从82.39％降至48.07％,有效提高了复合材料的含水率及保湿性;BC/N的拉伸强度和断裂伸长率较BC和Non有明显提高;MTT结果显示该材料具有良好的生物相容性;抗菌实验表明载Ag的BC/N具有极佳的抗菌性,对大肠杆菌和金黄色葡萄球菌的抑菌率最大可达99.96％,99.93％.因此,该材料有望在医用敷料领域得到广泛应用.
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