在不添加高分子表面活性剂的条件下,采用一种简单的水热合成方法制备出 In(OH)3纳米材料,并应用于尿酸的非酶电化学检测.X射线衍射(XRD)和扫描电子显微镜(SEM)显示,样品具有较好结晶性和均匀的分级三维花状结构.实验发现,该材料在氢氧化钠溶液体系中对尿酸表现出良好的电催化活性,且相比于 In2 O3具有更好的电极稳定性.基于该材料修饰的电极对尿酸的检测极限为75 nmol/L(S/N＝3),线性检测范围上限为4．969×10－4 mol/L,灵敏度高达301．3μA?mmol/L?cm2,具有良好的选择性.
Nanostructured Indium hydroxide (In(OH)3 )was synthesized through a facile hydrothermal route without any polymer surfactants,which was applied to the non-enzymatic electrochemical detection of uric acid (UA).The results characterized from X-ray diffraction (XRD)and scanning electron microscopy (SEM)indica-ted that the powders owned good crystallinity and uniform hierarchical 3-D flower-like structure.The experi-ment results revealed that the obtained material exhibited good electrocatalytic activity for the detection of UA in sodium hydroxide solution.In addition,compared with In2 O3 ,In(OH)3 showed higher electrode stability. The non-enzymatic electrochemical sensor was used in the detection of UA with a detection limit of 75 nmol/L (S/N = 3),a wide linear detection ranged up to 4.696×10-4 mol/L,a high sensitivity of 301.3μA?mmol/L?cm2 and good selectivity toward UA.
参考文献
| [1] | Kajal Jindal;Monika Tomar;Vinay Gupta.Inducing electrocatalytic functionality in ZnO thin film by N doping to realize a third generation uric acid biosensor[J].Biosensors & Bioelectronics: The International Journal for the Professional Involved with Research, Technology and Applications of Biosensers and Related Devices,2014:57-65. |
| [2] | Fenfen Zhang;Xiaoli Wang;Shiyun Ai;Zhengdong Sun;Qiao Wan;Ziqiang Zhu;Yuezhong Xian;Katsunobu Yamamoto.Immobilization of uricase on ZnO nanorods for a reagentless uric acid biosensor[J].Analytica chimica acta,20042(2):155-160. |
| [3] | Joseph Wang.Electrochemical Glucose Biosensors[J].Chemical Reviews,20082(2):814-825. |
| [4] | Yan, J.;Liu, S.;Zhang, Z.;He, G.;Zhou, P.;Liang, H.;Tian, L.;Zhou, X.;Jiang, H..Simultaneous electrochemical detection of ascorbic acid, dopamine and uric acid based on graphene anchored with Pd-Pt nanoparticles[J].Colloids and Surfaces, B. Biointerfaces,2013:392-397. |
| [5] | Wang SQ;Lu LP;Lin XQ.A selective voltammetric method for uric acid detection at a glassy carbon electrode modified with electrodeposited film containing DNA and Pt-Fe(III) nanocomposites[J].Electroanalysis,200420(20):1734-1738. |
| [6] | Chauhan, N.;Pundir, C.S..An amperometric uric acid biosensor based on multiwalled carbon nanotube-gold nanoparticle composite[J].Analytical Biochemistry: An International Journal of Analytical and Preparative Methods,20112(2):97-103. |
| [7] | Jindal, K.;Tomar, M.;Gupta, V..CuO thin film based uric acid biosensor with enhanced response characteristics[J].Biosensors & Bioelectronics: The International Journal for the Professional Involved with Research, Technology and Applications of Biosensers and Related Devices,20120(0):11-18. |
| [8] | In_(2)O_(3) nanowires as chemical sensors[J].Applied physics letters,200310(10):1613-1615. |
| [9] | Ahsanulhaq Qurashi;Muhammad Faisal Irfan;Mir Wakas Alam.In_2O_3 NANOSTRUCTURES AND THEIR CHEMICAL AND BIOSENSOR APPLICATIONS[J].Arabian journal for science and engineering, Section C. Theme issues,20101C(1C):125-145. |
| [10] | Sun, C.-L.;Chang, C.-T.;Lee, H.-H.;Zhou, J.;Wang, J.;Sham, T.-K.;Pong, W.-F..Microwave-assisted synthesis of a core-shell MWCNT/GONR heterostructure for the electrochemical detection of ascorbic acid, dopamine, and uric acid[J].ACS nano,201110(10):7788-7795. |
| [11] | Dong, J.;Hu, Y.;Zhu, S.;Xu, J.;Xu, Y..A highly selective and sensitive dopamine and uric acid biosensor fabricated with functionalized ordered mesoporous carbon and hydrophobic ionic liquid[J].Analytical and bioanalytical chemistry,20105(5):1755-1762. |
| [12] | Zhao, Dianyun;Fan, Dawei;Wang, Jinping;Xu, Caixia.Hierarchical nanoporous platinum-copper alloy for simultaneous electrochemical determination of ascorbic acid, dopamine, and uric acid[J].Mikrochimica Acta: An International Journal for Physical and Chemical Methods of Analysis,20157/8(7/8):1345-1352. |
| [13] | Huang JS;Liu Y;Hou HQ;You TY.Simultaneous electrochemical determination of dopamine, uric acid and ascorbic acid using palladium nanoparticle-loaded carbon nanofibers modified electrode[J].Biosensors & Bioelectronics: The International Journal for the Professional Involved with Research, Technology and Applications of Biosensers and Related Devices,20084(4):632-637. |
| [14] | Wang, JA;Zhang, WD.Sputtering deposition of gold nanoparticles onto vertically aligned carbon nanotubes for electroanalysis of uric acid[J].Journal of Electroanalytical Chemistry: An International Journal Devoted to All Aspects of Electrode Kinetics, Interfacial Structure, Properties of Electrolytes, Colloid and Biological Electrochemistry,20111/2(1/2):79-84. |
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