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黄酮羧酸类化合物是一类具有广泛的潜在生物活性与强的药理作用的黄酮类化合物,有良好的发展前景.文章概述了近年来黄酮羧酸类化合物的结构与功效关系、合成方法的研究进展,并对其稀土配合物的发展前景进行了展望,为今后黄酮羧酸类化合物及其稀土配合物的深入研究提供理论支持.

参考文献

[1] 邱关明,李幼荣,陈石燕,周兰香,李伟,张明.稀土对生物机体剂量效应机理的研究进展[J].稀土,2003(01):49-56.
[2] Sartor Luigi;Pezzato Elga;Dell'Aica Isabella;Caniato Rosamaria;Biggin Susan;Garbisa Spiridione .Inhibition of matrix-proteases by polyphenols: chemical insights for anti-inflammatory and anti-invasion drug design.[J].Biochemical Pharmacology,2002(2):229-237.
[3] 李荣,李俊.黄酮类化合物药理活性及其构效关系研究进展[J].安徽医药,2005(07):481-483.
[4] 黄华艺,查锡良.黄酮类化合物抗肿瘤作用研究进展[J].中国新药与临床杂志,2002(07):428-433.
[5] Walenta R;Muller-Peddinghaus R;Ban I et al.3-flavone carboxylic acid compounds and pharmaceutical compositions containing them[P].US Patent:4886806,1989-12-12.
[6] Zwaagstra M E;Timmerman H;Abdoelgafoe R S et al.Synthesis of carboxylated flavonoids as new leads for LTD4 antagonists[J].European Journal of Medicinal Chemistry,1996,31:861-874.
[7] Zwaagstra M E;Korthouwer R E M;Timmerman H et al.Synthesis of 3-and 5'-substituted flavone-8-carboxylic acids as 'three-armed' leukotriene CysLT1 receptor antagonists[J].European Journal of Medicinal Chemistry,1998,33:95-102.
[8] Doria G;Giraldi P;Lauria F et al.6-carboxy-flavone derivatives and process for their preparation[P].US Patent:4157334,1979-06-05.
[9] Valenti P;Bisi A;Rampa A;Gobbi S;Belluti F;Da-Re P;Cima L;Carrara M .Synthesis of flavone-2'-carboxylic acid analogues as potential antitumor agents.[J].Anti-Cancer Drug Design,1998(8):881-892.
[10] Shudo K .Flavone carboxylic acid derivatives[P].US Patent:4831052,1989-05-16.
[11] Kagechika H;Kawach E;Hashimoto Y et al.Retinobenzoic acids.2.structure-activity relationships of chalcone-4-carboxylic acids and flavone-4'-carboxylic acids[J].Journal of Medicinal Chemistry,1989,32:834-840.
[12] Gesson J P;Fonteneau N;Mondon M et al.7-carboxy-flavone derivatives preparation method and therapeutic use[P].US Patent:6965039,2005-11-15.
[13] Inoue H;Fukushima K;Nishiguchi I .3-methylflavone-8-carboxylic acid derivatives[P].US Patent:4634768,1988-06-08.
[14] Creuzet M H;Feniou C;Guichard F et al.4'-flavonecarboxylic acids and pharmaceutically acceptable derivatives their preparation,and their application[P].US Patent:4600788,1986-07-15.
[15] Jurg R,Pfister;Walter E,Wymann;Margery E.Schuler et al.Inhibition of histamine-induced gastric secretion by flavone-6-carboxylic acids[J].Journal of Medicinal Chemistry,1980,23:335-338.
[16] Shah D N;Parikh S K;Shah N M .Synthesis of flavone-and flavonol-6-carboxylic acid and related derivatives[J].Journal of the American Chemical Society,1955,77(08):2223-2224.
[17] Silva A M S;Pinto D C G A;Cavaleiro J A S .5-Hydroxy-2-(phenyl or styryl)chromones:one-pot synthesis and C-6,C-8 13C NMR assignments[J].Tetrahedron Letters,1994,35(32):5899-5902.
[18] Pinto D C G A;Silva A M S;Cavaleiro J A S J .Syntheses of 5-hydroxy-2-(phenyl or styryl)chromones and of some halo derivatives[J].Heteroatom Chemistry,1996,33:1887-1893.
[19] Bois F;Beney C;Mariotte A .A one-step synthesis of 5-hydroxyflavones[J].Synlett:Accounts and Rapid Communications In Synthetic Organic Chemistry,1999,9:1480-1482.
[20] 杨永刚,张宇,曹小平.(±)Cudraflavanone B及(±)-5-O-Methyl Cudraflavanone B的全合成研究[J].化学学报,2005(20):1901-1905.
[21] Hormi O E O;Moisio M R;Sund B C .Flavone-3-carboxylic acids,esters,and related compounds from β-chloroarylidenemalonates[J].Journal of Organic Chemistry,1987,52:5272-5274.
[22] Gesson J P;Fonteneau N;Mondon M et al.7-carboxy-flavone derivatives preparation method and therapeutic use[P].US Patent:6965039,2005-11-15.
[23] Varma R S;Boachell D H .The synthesis of flavones using novel surface functionalised silica supported metal and microwave[J].Journal of Chemical Research(Synopses),1998,12:348.
[24] George W Kabalk;Arjtm R Mereddy .Microwave-assisted synthesis of ftmctionalized flavones and hromones[J].Tetrahedron Letters,2005,46:6315-6317.
[25] 杨华.稀土配位化合物在医药领域应用概述[J].稀土,2007(02):95-98.
[26] Zhao DY.;Feng JL.;Chmelka BF.;Stucky GD.;Huo QS. .Nonionic triblock and star diblock copolymer and oligomeric surfactant syntheses of highly ordered, hydrothermally stable, mesoporous silica structures[J].Journal of the American Chemical Society,1998(24):6024-6036.
[27] Zhou J;Wang LF;Wang JY;Tang N .Synthesis, characterization, antioxidative and antitumor activities ofsolid quercetin rare earth(III) complexes[J].Journal of Inorganic Biochemistry: An Interdisciplinary Journal,2001(1):41-48.
[28] 吴锦绣,宋玉民,宋小利,杨声,冯小强.稀土芦丁配合物的合成、表征及荧光性质和抑菌活性的研究[J].化学研究与应用,2007(02):155-160.
[29] 宋玉民,吴锦绣.稀土芦丁配合物的合成、表征及与血清白蛋白的相互作用[J].无机化学学报,2006(12):2165-2172.
[30] 周晶,王进义,唐宁.槲皮素与金属Cd(Ⅱ) Sc(Ⅲ)配合物的合成及抗氧性研究[J].兰州大学学报(自然科学版),2001(01):123-125.
[31] 崔明珍;杨华;赵素娟 等.稀土化合物对MNNG致穿梭质粒pSP189 突变的影响[J].卫生毒理学杂志,1998,12(03):138-140.
[32] Masataka Yoshino;Miyako Haneda;Makoto Naruse et al.Prooxidant activity of flavonoids:copper-dependent strand breaks and the formatioin of 8-hydroxy-2'-deoxyguanosine in DNA[J].Molecular Genetics and Metabolism,1999,68:468-472.
[33] Giuseppe Galati;Omid Sabzevari;John X Wilson et al.Prooxidant activity and cellular effects of the phenoxyl mdicals of dietary flavonoids and other polyphenolics[J].Toxicology,2002,177:91-104.
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