膦配体钌配合物催化阿维菌素氢化的研究

贵金属, 2008, 29(1): 1-4. doi: 10.3969/j.issn.1004-0676.2008.01.001

膦配体钌配合物催化阿维菌素氢化的研究

熊晓东 ^1, , 吴松 ^2, , 王胜国 ^3, , 梁敬博 ^4,

1.有研亿金新材料股份有限公司,北京有色金属研究总院,北京,100088

2.有研亿金新材料股份有限公司,北京有色金属研究总院,北京,100088

3.有研亿金新材料股份有限公司,北京有色金属研究总院,北京,100088

4.有研亿金新材料股份有限公司,北京有色金属研究总院,北京,100088

关键词：催化化学 , 均相催化 , 钌配合物 , 阿维菌素 , 氢化

Study on the Hydrogenation of Avermectin Catalyzed by Phosphine Ligand Ruthenium Complexes

作者合成了4种膦配体钌配合物,并将它们应用于催化阿维菌素的氢化反应中,研究了其催化活性与选择性,并考察了温度、压力和反应时间对催化反应的影响.结果表明,RuCl2(PPh3)3、RuH(COOCH3)(PPh3)3有一定的催化性能;当氢气压力1MPa,温度60℃,反应6h,RuCl2(PPh3)3的催化效果较好;使用钌配合物催化阿维菌素的氢化反应能降低伊维菌素的生产成本.

参考文献

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材料期刊网

膦配体钌配合物催化阿维菌素氢化的研究

Study on the Hydrogenation of Avermectin Catalyzed by Phosphine Ligand Ruthenium Complexes

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