以陶瓷微滤膜过滤肌苷发酵液,考察了操作参数对膜通量的影响,结果表明,在pH为3.5,温度70℃,压差0.1 MPa,错流速度为3.25 m/s条件下操作,有利于提高膜通量;分析了膜的污染行为,在此基础上,获得了有效的膜清洗方法为:以质量分数为1%NaOH和0.2%NaClO混合溶液清洗膜40 min后,再以0.5%的HNO3溶液清洗5 min,膜通量可迅速恢复.研究表明,采用陶瓷微滤技术来处理肌苷发酵液是完全可行的.
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