介绍近年来在医药领域广泛应用的合成生物降解高分子材料的主要种类、结构特点、降解性质及制备方法;材料生物降解机理和主要的影响因素以及作为新型药物载体材料的应用前景.
参考文献
[1] | Woodland J H et al.Long-acting delivery systems for narcotic antagonists.1[J].Journal of Medicinal Chemistry,1973,16(08):897-901. |
[2] | 李曹,王远亮.聚乳酸制备研究进展[J].国外医学(生物医学工程分册),2002(06):274-278. |
[3] | Lewis D H.Controlled release of bioactive agents from lactide/glycolide polymers, in Biodegradable Polymers as Drug Delivery Systems[M].M. Chasin and R. Langer, Editors,1990 |
[4] | Koosha F;R.H. Muller;S.S. Davis .Polyhydroxybutyrate as a drug carrier[J].Critical Reviews in Therapeutic Drug Carrier Systems,1989,6(02):117-30. |
[5] | 魏民,宋艳秋,常津,姚康德.新型药物载体--半固态聚原酸酯的研究进展[J].中国药学杂志,2000(03):150-152. |
[6] | 陈先红,郑建华.生物降解高分子材料--聚酸酐的研究进展[J].高分子材料科学与工程,2003(03):31-34,39. |
[7] | Leong K W;V. Simonte;R. Langer .Synthesis of polyanhydrides: Melt-polycondensation, dehydrochlorination, and dehydrative coupling[J].Macromolecules,1987,20:705-12. |
[8] | Allcock H R .The synthesis of functional polyphosphazenes and their surfaces[J].Applied Organometallic Chemistry,1998,12:659-66. |
[9] | Bezemer I. M.;Weme P. O. .Amphiphilic poly(ether ester amide) multiblock copolymers as biodegradable matrices for the controlled release of proteins[J].Journal of biomedical materials research, Part B. Applied biomaterials,2000(1):8-17. |
[10] | Jeong B.;Kim SW.;Bae YH. .Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers[J].Journal of Controlled Release: Official Journal of the Controlled Release Society,2000(1/2):155-163. |
[11] | Ronneberger B et al.In vivo biocompatibility study of ABA trublock copolymers consisting of poly (L-lactic-co-glycolic acid ) A blocks attached to central poly(oxyethylene) B blocks[J].Journal of Biomedical Materials Research,1996,30(01):31-40. |
[12] | Helder J et al.Copolymers of DL-lactic acid and glycin[J].Macromolecular Rapid Communications,1986,7(04):193-8. |
[13] | Holland S J;B J Tighe;P L Gould .Polymers for biodegradable medical devices. 1. The potential of polyesters ascontrolled macromolecular release systems[J].Journal of Controlled Release,1986,4:155-80. |
[14] | 张粉艳,郝红,梁国正.应用于药物控释系统中的生物降解高分子材料[J].离子交换与吸附,2003(02):189-192. |
[15] | Y Sun;D .C. Watts;J.R. Johnson.Biodegradable drug delivery systems[J].American Pharmaceutical Review,2001:27-36. |
[16] | 王杰,张强,易翔,曹栋,黎洪珊,魏树礼.表面修饰对载环孢菌素A聚乳酸纳米粒[J].北京医科大学学报,2000(03):235-238. |
[17] | 吴诚,钟延强,刘善奎.干扰素缓释给药系统的研究进展[J].药学实践杂志,2003(02):87-89. |
[18] | Perets A;Baruch Y;Weisbuch F .Enhancing the vascularization of three-dimensional porous alginate scaffolds by incorporating controlled release basic fibroblast growth factor microsphere[J].BioMedical Master res,2003,65(04):489-97. |
[19] | Khanna C;Prehn J;Hayden D et al.[J].Clinical Cancer Research,2002,8(07):2406-12. |
[20] | Y Luo;G.D. Prestwich .Synthesis and selective cytotoxicity of a hyaluronic acid-antitumor bioconjugate[J].Bioconjugate Chemistry,1999,10:755-63. |
[21] | Tang H;Una M K;Mary L H .Biological potency of microsphere encapsulated plasmid DNA[J].Journal of Controlled Release,2000,69:249. |
[22] | Cohen H;Levy RJ;Gao J;Fishbein I;Kousaev V;Sosnowski S;Slomkowski S;Golomb G .Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles.[J].Gene therapy,2000(22):1896-1905. |
[23] | 何勤,张志荣,刘戟,苏敏,张华,卢懿,聂飞,罗鹏.载TK基因聚丙交酯乙交酯纳米粒的制备及有关性质研究[J].生物医学工程学杂志,2002(01):30-33. |
[24] | 刘丽;李晨曦;何炳林 .生物降解高分子纳米球的制备[J].应用化学,1999,16(05):69-72. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分:
-
10%
-
20%
-
30%
-
40%
-
50%