本文利用杜仲对成骨的有利作用,采用浸提法将杜仲叶水溶性提取物载入到磷酸钙骨水泥(CPC)中,旨在通过CPC协同形成高效骨修复材料.用XRD和FIIR检测了其理化特性,同时也测量含杜仲叶提取物CPC的抗压强度、水中溶解度和pH值.实验结果显示杜仲叶提取物载入对CPC固化时间、抗压强度和pH值变化、相组成均无明显影响,这些反映了杜仲叶提取物的载入对CPC的理化特性无明显影响.
参考文献
| [1] | Brown WE;Chow LC.A new calcium phosphate cement water-setting cement[A].Westervillie,OH:American Ceramic Society,1986:352-379. |
| [2] | Ito A;Kawamura H;Otsuka M et al.[J].Materials Science and Engineering C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS,2002,22(01):21-25. |
| [3] | Jansen JA;Vehof JWM;Ruhe PQ;Kroeze-Deutman H;Kuboki Y;Takita H;Hedberg EL;Mikos AG .Growth factor-loaded scaffolds for bone engineering[J].Journal of Controlled Release: Official Journal of the Controlled Release Society,2005(1/3):127-136. |
| [4] | Lin FH;Liao CJ;Chen KS;Sun JS;Lin CY .Preparation of betaTCP/HAP biphasic ceramics with natural bone structure by heating bovine cancellous bone with the addition of (NH(4))(2)HPO(4).[J].Journal of biomedical materials research, Part B. Applied biomaterials,2000(2):157-163. |
| [5] | Daculsi G;Weiss P;Bouler JM et al.Biphasic calcium phosphate/hydrosoluble polymer composites:A new concept for bone and dental substitution biomaterials[J].Bone,1999,25(02):59-61. |
| [6] | Chen YS .Calvarial bone response to a tricalcium phosphate-genipin crosslinked gelatin composite.[J].Biomaterials,2005(16):3065-3074. |
| [7] | Braye F.;Jallot E.;Oudadesse H.;Weber G.;Deschamps N. Deschamps C.;Frayssinet P.;Tourenne P.;Tixier H.;Terver S.;Lefaivre J.;Amirabadi A.;Irigaray JL. .RESORPTION KINETICS OF OSSEOUS SUBSTITUTE - NATURAL CORAL AND SYNTHETIC HYDROXYAPATITE[J].Biomaterials,1996(13):1345-1350. |
| [8] | 胡金家,王曼莹.杜仲叶提取物对体外培养的成骨细胞代谢功能调节研究[J].中国中医基础医学杂志,2001(04):48-49. |
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