采用尼罗红(Nile red)染料为探针,利用吸收和发射光谱研究了具有不同烷芳基结构的可聚合阳离子型Hydrotropes(PCHs)的溶液性质,结果表明其在水溶液中易发生自缔合行为并具有两个阈值浓度:分子开始自缔合的临界浓度(CAC)(10-1-10-2 mol/L),开始大幅度提高助溶作用的最小助溶浓度(MHC) (＞10-1 mol/L),两阈值浓度均随化合物分子结构中的疏水基团尺寸的增大而减小.两亲化合物聚集体的微环境极性测定的结果显示,其极性比表面活性剂胶束高,并且随着化合物浓度的增大不断下降,表明形成的聚集体结构比较疏松,且其分子堆砌密度随聚集体的增大而逐步升高.此外,通过自由基聚合得到相应的两亲聚合物仍保留Hydrotrope原有的性能,并具有更显著的助溶作用.
参考文献
| [1] | Neuberg C .Hydrotropic phenomena[J].Journal of the Chemical Society,1916,110:555-559. |
| [2] | Neuberg C .Hydrotropy[J].Biochemische Zeitschrift,1916,76:107-108. |
| [3] | Gaikar V;Sharma M .Separations with hydrotropes[J].Separation and Technology,1993,3(01):2-11. |
| [4] | Kabir-ud-Din;Parveen, N;Naqvi, AZ .Hydrotropic Behavior of Sodium Salicylate in Presence of Additives[J].Journal of Dispersion Science and Technology,2009(10):1500-1505. |
| [5] | Jain P;Goel A;Sharma S et al.Solubility enhancement techniques with special emphasis on hydrotrophy[J].International Journal of Pharma Professional's Research,2010,1(01):34-45. |
| [6] | Shukla M;Rathore P;Jain A et al.Enhanced solubility study of glipizide using different solubilization techniques[J].International Journal of Pharmacy and Pharmaceutical Sciences,2010,2(02):46-48. |
| [7] | Kim JY;Kim S;Papp M;Park K;Pinal R .Hydrotropic solubilization of poorly water-soluble drugs.[J].Journal of Pharmaceutical Sciences,2010(9):3953-3965. |
| [8] | Travis K.Hodgdon;Eric W.Kaler .Hydrotropic solutions[J].Current opinion in colloid & interface science,2007(3):121-128. |
| [9] | Friberg SE;Lochhead RV;Blute I;Warnheim T .Hydrotropes - Performance chemicals[J].Journal of Dispersion Science and Technology,2004(3):243-251. |
| [10] | 袁钊,曾毅,陈金平,李迎迎,韩永滨,李嫕.以尼罗红为探针对新型两亲性树枝形聚合物微环境的研究[J].影像科学与光化学,2010(05):343-353. |
| [11] | 姜小明,宋磊,赵濉.荧光探针法研究双子型阳离子表面活性剂与明胶的相互作用[J].影像科学与光化学,2012(03):175-181. |
| [12] | Sang Cheon Lee;Kang Moo Huh;Jaehwi Lee .Hydrotropic Polymeric Micelles for Enhanced Paclitaxel Solubility:In Vitro and In Vivo Characterization[J].Biomacromolecules,2007(26):202-208. |
| [13] | Lee SC.;Acharya G.;Lee J.;Park K. .Hydrotropic polymers: Synthesis and characterization of polymers containing picolylnicotinamide moieties[J].Macromolecules,2003(7):2248-2255. |
| [14] | Gui-xia Wang,Yu-xi Zhang,Fei-peng Wu.CATIONIC SURFMERS WITH BENZYL GROUPS: SYNTHESIS AND COPOLYMERIZATION WITH ACRYLAMIDE[J].高分子科学（英文版）,2011(03):352-359. |
| [15] | 王桂霞,李万刚,张玉玺,李振泉,宋新旺,曹绪龙,吴飞鹏.阳离子型共聚物 AM/DMBAC 疏水微嵌段结构的分析[J].高分子学报,2010(04):435-441. |
| [16] | May W E;Wasik S P;Freeman D H .Determination of the solubility behavior of some polycyclic aromatic hydrocarbons in water[J].Analytical Chemistry,1978,50(07):997-1000. |
| [17] | Meyyappan N;Gandhi NN .Solubility and mass transfer coefficient enhancement of benzyl acetate in water through hydrotropy[J].Journal of Chemical and Engineering Data: the ACS Journal for Data,2004(5):1290-1294. |
| [18] | Neumann MG;Schmitt CC;Prieto KR;Goi BE .The photophysical determination of the minimum hydrotrope concentration of aromatic hydrotropes[J].Journal of Colloid and Interface Science,2007(2):810-813. |
| [19] | 姜永才;吴世康 .在胶束形成前染料分子的能量转移与预胶束基本性质的研究[J].化学学报,1990,48(05):447-451. |
| [20] | Deye J F;Berger T A;Anderson A G .Nile red as a solvatochromic dye for measuring solvent strength in normal liquids and mixtures of normal liquids with supercritical and near critical fluids[J].Analytical Chemistry,1990,62(06):615-622. |
| [21] | 李晶,吴飞鹏,王尔鉴.Hydrotrope型两亲化合物的合成和自缔合研究[J].影像科学与光化学,2009(04):287-295. |
| [22] | Jing Li,Fei-peng Wu,Er-jian Wang.STUDIES ON SELF-ASSOCIATIVE BEHAVIOR OF A NOVEL CATION AMPHIPHILIC POLYMER[J].高分子科学（英文版）,2009(04):593-596. |
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