表面等离子共振光谱(Surface Plasmon Resonance,SPR)是近年来得到快速发展的一门技术.它是一种无标记的、可用于实时定量检测某些固定于传感芯片上的组分与被结合物种间的绑定亲合度(binding affinity)、且可用于对相对小量物质进行检测的重要手段.由于它可方便地研究不同生物或化学物种的有关反应与动力学问题,因此具有重要的实用意义,受到广泛关注和重视.本文对有关等离子共振现象的形成及其作为敏感检测手段的机制、原理和改进等问题作了简要的介绍.
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