随着科技的发展和社会的进步,食品安全问题越来越受到关注.糖精钠作为一种食品添加剂,其非法添加事件时有发生,因此,有必要找到一种快速准确检测糖精钠的方法.荧光分子探针因具有灵敏度高、选择性好、响应时间短的优点,其在分析化学检测中的应用越来越广泛.本文设计并合成了一种含蒽荧光团的氮杂15-冠一5化合物,利用分子识别的原理,该目标化合物能够特异性识别溶液中的糖精钠,使溶液的荧光强度发生变化,具有肉眼可见、易于观察的特点,该方法为食品中糖精钠的快速检测提供了一种可行的手段.
With the development of technology and the progress of society,the food safety problem gains increasing attention.Saccharin sodium,as one kind of food additives,is occasionally reported as illegal additions.Thus it is necessary to find a rapid and accurate method for the detection of saccharin sodium.The fluorescence molecular probe has gained a widely application in analytical chemistry determination due to its advantages such as high sensitivity,good selectivity and short response time.In this paper,a novel compound contained an anthracene fluorophore and an aza-15-crown-5 group was designed and synthesized.Based on the molecular recognition,the compound could specifically recognize the saccharin sodium in solution,resulting in the changes of fluorescence intensity.What's more,the phenomenon is visible and easy to be observed.The method provides a practicable strategy for rapid determination saccharin sodium in food.
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