C6位氧化细菌纤维素的制备及结构表征

高分子材料科学与工程, 2014, 30(12): 70-75.

C6位氧化细菌纤维素的制备及结构表征

廖世波 ^1, , 赖琛 ^2, , 奚廷斐 ^3, , 盛立远 ^4, , 董稳 ^5, , 王巧莉 ^6, , 张志雄 ^7,

1.北京大学深圳研究院人体组织再生与修复深圳重点实验室,广东深圳518057

2.北京大学深圳研究院人体组织再生与修复深圳重点实验室,广东深圳518057

3.北京大学深圳研究院人体组织再生与修复深圳重点实验室,广东深圳518057

4.北京大学深圳研究院人体组织再生与修复深圳重点实验室,广东深圳518057

5.上海方宇工业设计有限公司,上海201815

6.北京大学深圳研究院人体组织再生与修复深圳重点实验室,广东深圳518057

7.北京大学深圳研究院人体组织再生与修复深圳重点实验室,广东深圳518057

基金项目: 国家重大科学研究计划项目(2012CB933603) 浙江省新苗人才计划项目(2012R413046) 深圳市科技计划基础研究项目(JCYJ20130402164725011)

关键词：细菌纤维素 , 2,2,6,6-四甲基-1-哌啶酮 , 选择性氧化 , 羧基含量

Preparation and Structure Characterization of C6-Oxidated Bacterial Cellulose

Keywords： bacterial cellulose , 2,2,6,6-tetramethyl-1-piperidinyloxy , selective oxidation , carboxyl con tent

为了改善细菌纤维素的生物降解性,采用2,2,6,6-四甲基-1-哌啶酮(TEMPO)/NaBr/NaClO体系对细菌纤维素进行氧化,探讨了NaClO和TEMPO用量及反应时间对反应的影响,利用电导滴定、红外光谱、13C-核磁共振、X射线衍射和透射电子显微镜对固体产物进行了表征.结果显示,细菌纤维素取1 g,0.6 mol/L NaClO 8 mL,TEMPO 0.016 g,NaBr0.1g,反应8h可以获得羧基含量较高的氧化细菌纤维素(羧基含量为1.04 mol/kg).红外光谱和13C-核磁共振波谱共同证明细菌纤维素C6位伯醉羟基被选择性催化氧化成了羧基,X射线衍射结果表明氧化后细菌纤维素的结晶结构没有发生明显改变,TEM结果显示氧化后细菌纤维素的蚋米网状结构得到保留.利用TEMPO/NaBr/NaClO体系可以获得氧化度较高的微观结构无损伤的氧化型细菌纤维素.

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