基因芯片技术是建立在杂交序列基本理论上的分子生物学技术,它以一种全面、综合和系统的思维方式研究生命现象.基因芯片技术可以完整地研究整个细胞或器官全部基因变化,可以通过基因分析发现对电离辐射的基因反应差异,从而建立一种新的分子放射生物学方法.综述了基因芯片技术及应用领域,重点介绍了基因芯片技术在辐射治疗癌症中的应用.概述了重离子治疗肿瘤优于其它射线的原因.展望了利用基因芯片技术的优势探索肿瘤经重离子辐照前、中、后期的生物学效应.
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