欢迎登录材料期刊网

材料期刊网

高级检索

采用液相共沉淀法分别制备了不同比例的纳米羟基磷灰石(HAP)/壳聚糖(CS)-海藻酸钠(Alg)复合材料,在利用XRD、SEM及EDS对制备的复合材料进行分析研究的基础上,考察了复合材料的力学性能.研究结果表明,复合材料内部结合致密,有机相与无机相融为一体,羟基磷灰石颗粒结晶较好,形状为类球状,平均粒径为20nm左右,颗粒分布相对均匀;HAP与CS-Alg质量比的变化直接影响复合材料内HAP颗粒的结晶、粒径及分散性.当HAP与CS-Alg的质量比为50∶50时,复合材料的均一性、致密性最佳,抗压强度最大可达46.5 MPa.EDS分析发现复合材料中仅含微量的钠和钾元素,钙、磷原子比约为1.75,属于富钙型的HAP.

参考文献

[1] Pang Xiaofeng;Zeng Hongjuan;Liu Jialie .The properties of nanohydroxyapatite materials and its biological effects[J].Mater Sci Appl,2010,1(02):81.
[2] 王韵晴;卢婷利;赵雯 等.骨组织工程支架材料的研究进展[J].材料导报:综述篇,2011,25(02):125.
[3] Patricia C Salgadol et al.Bone remodeling,biomaterials and technological applications:Revisiting basic concepts[J].J Biomater Nanobiotechn,2011,2(03):318.
[4] 吕彩霞,姚子华.羟基磷灰石/壳聚糖复合材料研究进展[J].化工进展,2006(07):755-759.
[5] 辛雷,苏佳灿.人工骨修复材料的现状与展望[J].创伤外科杂志,2011(03):272-275,284.
[6] Junjie Li;Hong Sun;Da Sun .Biomimetic multicomponent polysaccharide/nano-hydroxyapatite composites for bone tissue engineering[J].Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides,2011(4):885-894.
[7] 魏靖明,张志斌,冯华,林松,张琨.海藻酸钠作为药物载体材料的研究进展[J].化工新型材料,2007(08):20-22.
[8] Khaled R Mohamed;Zenab M El-Rashidy .Preparation and characterization of nano hydroxyapatite/polymeric composites materials[J].Materials Chemistry and Physics,2011,130(01):561.
[9] 肖海军,薛锋,何志敏,金粉勤,沈玉春.纳米羟基磷灰石/羧甲基壳聚糖-海藻酸钠复合骨水泥的生物相容性与体内降解研究[J].生物医学工程研究,2011(03):159-163.
[10] Wang, L.;Weng, L.;Song, S.;Zhang, Z.;Tian, S.;Ma, R. .Characterization of polyetheretherketone-hydroxyapatite nanocomposite materials[J].Materials Science & Engineering, A. Structural Materials: Properties, Misrostructure and Processing,2011(10/11):3689-3696.
[11] Rangasamy Jayakumar et al.Chitin scaffolds in tissue engineering[J].INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2011,12(03):1876.
[12] Wang Feng;Guo Enyan;Song Enmin .Structure and properties of bone-like-nanohydroxyapatite/gelatin/polyvinyl alcohol composites[J].Adv Biosci Biotechn,2010,1(03):185.
[13] Rajkumar M;Meenakshisundaram N;Rajendran V .Development of nanocomposites based on hydroxyapatite/sodium alginate:Synthesis and characterization[J].Materials Characterization,2011,62(05):469.
[14] Fathi M H;Hanifi A;Mortazavi V .Preparation and bioactivity evaluation of bone-like hydroxyapatite nanopowder[J].Journal of Materials Processing Technology,2008,202(01):536.
上一张 下一张
上一张 下一张
计量
  • 下载量()
  • 访问量()
文章评分
  • 您的评分:
  • 1
    0%
  • 2
    0%
  • 3
    0%
  • 4
    0%
  • 5
    0%