纳米羟基磷灰石的制备及吸附与矿化效应

功能材料, 2004, 35(z1): 2271-2274.

纳米羟基磷灰石的制备及吸附与矿化效应

吕奎龙 ^1, , 张久兴 ^2, , 孟祥才 ^3, , 周美玲 ^4, , 李星逸 ^5,

1.北京工业大学,新型功能材料教育部重点实验室,北京,100022;佳木斯大学,生物医学材料省级重点实验室,黑龙江,佳木斯,154007

2.北京工业大学,新型功能材料教育部重点实验室,北京,100022

3.佳木斯大学,生物医学材料省级重点实验室,黑龙江,佳木斯,154007

4.北京工业大学,新型功能材料教育部重点实验室,北京,100022

5.佳木斯大学,生物医学材料省级重点实验室,黑龙江,佳木斯,154007

关键词：纳米羟基磷灰石 , 吸附 , 再矿化

Synthesized and theabsorption and mineralization effect of nano-hydroxyapatite

为了研究纳米HA的生物学效应,本文采用Ca(H2PO4)2·H2O均匀沉淀反应体系制备纳米HA.XRD与TEM分析结果表明:干燥态HA粒子为低结晶度、(5～20nm)×60nm针状:烧结态的粒子呈球状、粒径＜100nm.生物学实验结果表明:不同形态的HA溶液对唾液蛋白均有吸附,吸附率达32.74%;对葡聚糖的吸附率高达到97.38%.人工釉质龋经纳米HA溶液矿化10天后硬度值提高一倍、已恢复到脱矿前的79%左右;扫描电镜观测表明:矿化处理后的牙釉面表面有片状矿物盐沉积、釉面孔隙减小、釉质表面光滑,进一步表明纳米HA对人工龋有明显的再矿化作用.

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纳米羟基磷灰石的制备及吸附与矿化效应

Synthesized and theabsorption and mineralization effect of nano-hydroxyapatite

参考文献