为了改善透磷灰石骨水泥的性能,使其更适用于临床,在传统透磷灰石骨水泥的基础上引入了α-TCP,测定了其理化性质,并进行了肌肉植入实验.α-TCP的引入延长了透磷灰石骨水泥的固化时间,提高了骨水泥的抗溃散能力,在一定程度上提高了透磷灰石骨水泥的pH值.植入肌肉实验对照表明,植入初期均有轻微炎症,含α-TCP骨水泥的炎症略轻,植入后期炎症反应均消失.
To improve the performance of brushite bone cement to make it more applicable to clinical,α-TCP is introduced to brushite bone cement, its physics and chemistry performance is examined and the muscle implantion test has been done. The introduction of orTCP extends the solidified time of the brushite bone cement, improves scatteres resistance of the bone cement, and increases the pH value of bone cement to some extent. The muscle implantion test control shows that there is a slight inflammation both at the initial implant time, the bone cement containing α-TCP has slighter inflammation, inflammation disappeares at the later implant.
参考文献
| [1] | Brown W E;Chow L C.A new calcium phosphate water setting cement[J].Gem Res Prog,1986:352. |
| [2] | Toshifumi S;Wetzel E .Microsphere-filled light weight calcium phosphate cements[J].Journal of Materials Science,1994,29(19):145. |
| [3] | Takechi M;Miyamoto Y;Ishikawa K;Nagayama M;Kon M;Asaoka K;Suzuki K .Effects of added antibiotics on the basic properties of anti-washout-type fast-setting calcium phosphate cement.[J].Journal of biomedical materials research, Part B. Applied biomaterials,1998(2):308-316. |
| [4] | 杨洪,赵培正.液相沉淀法制备β-磷酸三钙[J].河南师范大学学报(自然科学版),2007(01):122-124. |
| [5] | Driessens F C M et al.Formulation and setting times of some calcium orthophosphate cements:A pilot study[J].Mater Sci Mater in Med,1993,4(05):503. |
| [6] | 周磊,闫景龙,胡春杰.聚磷酸钙纤维/磷酸钙骨水泥复合材料修复骨缺损的实验研究[J].中国脊柱脊髓杂志,2006(11):851-855,后插4-后插5. |
- 下载量()
- 访问量()
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%