血管内支架是治疗心血管疾病最有效的方法之一,普通金属支架易导致支架内再狭窄,生物可降解血管支架的暂时存留性明显降低了支架内再狭窄的发生.简述了支架的加工工艺,同时对生物可降解血管支架的研究现状进行了分类论述,包括生物可降解膜被覆金属支架、载药生物可降解膜被覆金属支架(药物涂层支架)、完全生物可降解性冠状动脉支架和载药生物可降解性冠状动脉支架.最后展望了生物可降解血管支架的发展趋势.
参考文献
| [1] | Grüntzig A R;Senning A et al.Nonopeartive dilatation of coronary artery stenosis:Percutaneous transluminal coronary angioplasty[J].New England Journal of Medicine,1979,301(02):61. |
| [2] | Sigwart U;Puel J;Mirkovitch V et al.Intravascular stents to prevent occlusion and restenosis after transluminal graf-ting[J].Radiology,1986,160:723. |
| [3] | Stack T E;Califf R M;Phillips H P et al.Interventional cardiac catheterization at Duke medical center[J].American Journal of Cardiology,1998,62(Suppl F):3. |
| [4] | 黄莹莹,齐民,杨大智,王昌明.冠脉支架表面PLGA涂层制备及其血液相容性研究[J].功能材料,2006(03):411-414. |
| [5] | 赵慧强,郭文怡,贾国良,王海昌,李虎,李飞,秦涛,程如峰,张志辉,梁军,王晓燕.雷帕霉素洗脱支架置入动物体内后的支架内皮化进程[J].中国医师杂志,2006(01):45-46,51. |
| [6] | Hoffmann R;Mintz G S;Haager P K et al.Unexpected sensitization routes and general frequency of contact allergies in an elderly stented Sewdish population[J].Contact Dermatitis,2007,56(06):338. |
| [7] | Jin-Jun Qiu;Zhao-Xuan He;Cheng-Mei Liu;Xiao-Dong Guo;Qi-Xing Zheng .Crosslinking property of an oligomeric unsaturated phosphoester used as a potential injectable biomaterial[J].Biomedical materials,2008(4):044107-1-044107-6-0. |
| [8] | Yanxia Zhu;Tianqing Liu;Kedong Song;Bo Jiang;Xuehu Ma;Zhanfeng Cui .Collagen-chitosan Polymer As A Scaffold For The Proliferation Of Human Adipose Tissue-derived Stem Cells[J].Journal of Materials Science. Materials in Medicine,2009(3):799-808. |
| [9] | 顾兴中,倪中华.微孔结构血管支架的激光切割工艺[J].华中科技大学学报（自然科学版）,2007(z1):143-146. |
| [10] | 张勇,强华,郝静,黄楠,杜全兴.血管支架筋宽误差分析及激光加工工艺优化[J].西南交通大学学报,2007(02):229-233. |
| [11] | 黄远,田筝,刘文西,张君奎.加工工艺对医用心血管支架生物相容性的影响[J].天津大学学报,2003(03):374-379. |
| [12] | 蒙红云,廖健宏,官邦贵,张庆茂,周永恒.心血管支架的光纤激光切割工艺[J].中国激光,2007(05):733-736. |
| [13] | 刘清欣,王建华,颜志平,刘嵘,钱晟.镍钛记忆合金血管内支架的实验研究[J].中国临床医学,2006(04):542-544. |
| [14] | Tepe G;Schmehl J;Wendel HP;Schaffner S;Heller S;Gianotti M;Claussen CD;Duda SH .Reduced thrombogenicity of nitinol stents - In vitro evaluation of different surface modifications and coatings[J].Biomaterials,2006(4):643-650. |
| [15] | Leng Y X;Chen J Y;Huang N et al.The biocompatibility of the tantalum and tantalum oxide films synthesized by pulse metal vacuum arc source deposition[J].Nuclear Instruments and Methods in Physics Research,2006,242:30. |
| [16] | Hagspiel KD;Leung DA;Nandalur KR;Angle JF;Dulai HS;Spinosa DJ;Matsumoto AH;Christopher JM;Ahmed H;Berr SS .Contrast-Enhanced MR Angiography at 1.5 T After Implantation of Platinum Stents: In Vitro and In Vivo Comparison with Conventional Stent Designs.[J].American Journal of Roentgenology,2005(1):288-294. |
| [17] | 沈阳,王贵学,全学军,俞青松.NiTi合金血管内支架表面改性及其生物相容性研究[J].中国医疗器械杂志,2006(01):3-6,38. |
| [18] | Tijima R;Ikari Y;Amiya E et al.The impact of metallic allergy on stent Implantation:metal allery and recurrence of in-stent rostenosis[J].International Journal of Cardiology,2005,104(03):319. |
| [19] | 刘晋,徐克,张曦彤,黄亘,张斌.自制被覆聚氨酯膜与非覆膜不锈钢支架在动脉系统应用的实验对照研究[J].中国医学影像技术,2003(02):129-132. |
| [20] | 皇甫强,于振涛,罗丽娟,牛金龙,张亚峰,袁思波,王莹.钛合金血管内支架研究进展[J].钛工业进展,2007(01):29-31. |
| [21] | 李玉宝.生物医学材料[M].北京:化学工业出版社,2003 |
| [22] | 马丽君,张广增,刘素艳.冠状动脉涂层支架的药物选择及其应用评价[J].中国煤炭工业医学杂志,2004(09):802-803. |
| [23] | 曹晶茗,肖践明,刘中梅,刘蓉,蔡红雁,张云红,许峰,郭涛,韩明华.应用冠脉血管内超声评价药物涂层支架置放后再狭窄及血管内膜增生[J].介入放射学杂志,2007(10):657-660. |
| [24] | 陈立娟,马根山,冯毅,沈成兴,陈忠,章晓国.紫杉醇药物涂层支架治疗左前降支病变临床研究[J].东南大学学报（医学版）,2006(06):423-426. |
| [25] | 马长生,聂绍平.药物洗脱支架--现状与前景[J].中国医刊,2004(04):6-9. |
| [26] | Agrawal C M;Haas K F;Leopold D A et al.Evaluation of poly(L-lactic acid) as material for intravascular polymeric stents[J].Biomaterials,1992,13:176. |
| [27] | 王春宁,高润霖,程树军,宋来凤,郑金刚,訾振军,阮英茆,孟亮.聚-乳酸-乙醇酸涂层冠状动脉支架的生物相容性实验研究[J].中华心血管病杂志,2003(07):528-531. |
| [28] | 刘斌,李淑梅,张基昌,史永锋.生物可降解高分子材料载内皮前体细胞CD34抗体涂层支架防治犬冠脉再狭窄的研究[J].中国实验诊断学,2007(03):369-371. |
| [29] | 吴玉玉,游庆军,齐晓薇.PDS小血管支架在犬体内降解的实验研究[J].山东医药,2009(06):40-41. |
| [30] | Zartner P;Cesnjevar R;Singer H;Weyand M .First successful implantation of a biodegradable metal stent into the left pulmonary artery of a preterm baby.[J].Catheterization and cardiovascular interventions: Official journal of the Society for Cardiac Angiography & Interventions,2005(4):590-594. |
| [31] | Vogt F;Stein A;Rettemeier G et al.Long-term assessment of a novel biodegradable paclitaxel-eluting coronary polylactide stent[J].European Heart Journal,2004,25(15):1330. |
| [32] | 李绮,汤岩,谭丽丽,颜廷亭,张炳春,杨柯.可降解镁合金表面载药涂层的制备和性能[J].材料研究学报,2009(03):300-304. |
| [33] | Uurto I;Mikkonen J;Parkkinen J;Keski Nisula L;Nevalainen T;Kellomaki M;Tormala P;Salenius JP .Drug-eluting biodegradable poly-d/l-lactic Acid vascular stents: an experimental pilot study.[J].Journal of endovascular therapy: an official journal of the International Society of Endovascular Specialists,2005(3):371-379. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%