欢迎登录材料期刊网

材料期刊网

高级检索

淀粉基(starch-based)材料是一类重要的生物降解聚合物,羟基磷灰石(HA)是人体骨骼的主要成分,以淀粉基材料为基体、以HA为增强材料的HA/淀粉基复合材料是一类新型的复合生物材料,其具有良好的生物相容性,在骨修复领域具有巨大的应用潜力.初步对该复合材料进行了归类,并介绍了其制备工艺、性能和应用等方面的研究近况,指出改进复合工艺、采用纳米级HA增强并进行表面改性是其发展趋势.

参考文献

[1] Lorcks J. .Properties and applications of compostable starch-based plastic material[J].Polymer Degradation and Stability,1998(1/3):245-249.
[2] Reis R L;Cunha A M .Starch and starch based thermoplastics[J].Encyclopedia of Material Science and Engineering,2001,10:8810.
[3] Reis R L;Cunha A M;Bevis M J.Mechanical behaviour of injection moulded starch based polymers[J].Polymers for Advanced Technologies,1996(07):784.
[4] KIM S H;Chin I J;Yoon J S .Mechanical properties of biodegradable blends of poly L-lactic acid and starch[J].Korean Polymer Journal,1998,6:422.
[5] Averous L;Boquillon N .Biocomposites based on plasticized starch.thermal and mechanical behavious[J].Carbohydrate Polymers,2004,56:111.
[6] Ke TY.;Sun XZ. .Physical properties of poly(lactic acid) and starch composites withvarious blending ratios[J].Cereal Chemistry,2000(6):761-768.
[7] Reis R L;Cunha A M.New degradable load-bearing biomaterials based on reinforced thermoplastic starch incorporating blends[J].Journal of Appl Med Polym,2000:1.
[8] Demirgoz D.;Mano JF.;Cunha AM.;Piskin E.;Reis RL.;Elvira C. .Chemical modification of starch based biodegradable polymeric blends: effects on water uptake, degradation behaviour and mechanical properties[J].Polymer Degradation and Stability,2000(2):161-170.
[9] Araujo M A;Vaz C M;Cunha A M et al.In-vitro degradation behaviour of starch/EVOH biomaterials[J].Polymer Degradation and Stability,2000,73(02):237.
[10] Reis R L;Mendes S C;Cunha A M et al.Processing and in-vitro degradation of starch/EVOH thermoplastic blends[J].Polymer International,1997,2(43):347.
[11] Mano JF.;Cunha AM.;Reis RL. .Effects of moisture and degradation time over the mechanical dynamical performance of starch-based biomaterials[J].Journal of Applied Polymer Science,2000(13):2345-2357.
[12] Araujo MA;Cunha AM;Mota M .Enzymatic degradation of starch-based thermoplastic compounds used in protheses: identification of the degradation products in solution.[J].Biomaterials,2004(13):2687-2693.
[13] Helena S.Azevedo;Francisco M.Gama;Rui L.Reis .In Vitro Assessment of the Enzymatic Degradation of Several Starch Based Biomaterials[J].Biomacromolecules,2003(6):1703-1712.
[14] Marques AP;Reis RL;Hunt JA .The biocompatibility of novel starch-based polymers and composites: in vitro studies.[J].Biomaterials,2002(6):1471-1478.
[15] Sandra C M;Reis R L;Yvonne P B.Biocompatibility testing of novel starch-based materials with potential application in orthopaedic.a preliminary study[J].Biomaterials,2001(22):2057.
[16] Gomes ME;Reis RL;Cunha AM;Blitterswijk CA;de-Bruijn JD .Cytocompatibility and response of osteoblastic-like cells to starch-based polymers: effect of several additives and processing conditions.[J].Biomaterials,2001(13):1911-1917.
[17] Marques A P;Reis R L;Hunt J A.Evaluation of the potential of starch-based biodegradable polymers in the activation of human inflammatory cells[J].Journal of Materials Science:Materials in Medicine,2003:167.
[18] Gomes ME;Ribeiro AS;Malafaya PB;Reis RL;Cunha AM .A new approach based on injection moulding to produce biodegradable starch-based polymeric scaffolds: morphology, mechanical and degradation behaviour.[J].Biomaterials,2001(9):883-889.
[19] Gomes M E;Godinho J S;Tchalamov D.Alternative tissue engineering scaffolds based on starch.processing methodologies,morphology,degradation and mechanical properties[J].Materials Science and Engineering C,2002:19.
[20] Mano J F;Sousa R A;Boesel L F et al.Bionert,biodegradable and injectable polymeric matric composites for hard tissue replacement.state of the art and recent development[J].Composites Science and Technology,2004,64:789.
[21] Pereira CS.;Reis RL.;Vazquez B.;San Roman J.;Cunha AM. .New starch-based thermoplastic hydrogels for use as bone cements or drug-delivery carriers[J].Journal of Materials Science. Materials in Medicine,1998(12):825-833.
[22] 戈进杰.生物高分子材料及其应用[M].北京:化学工业出版社,2002:48.
[23] 刘榕芳,肖秀峰,林岚云,陈古镛.水热电沉积羟基磷灰石涂层的研究[J].高等学校化学学报,2004(02):304-308.
[24] Ismael E;Carlos E;Mano J F.New partially biodegradable and bioactive acrylic bone cements based on starch blends and ceramic fillers[J].Biomaterials,2002(23):1883.
[25] Mano J F;Koniarova D;Reis R L.Thermal properities of themroplastic starch/synthetic polymer blends with potential biomedical applicability[J].Journal of Materials Science:Materials in Medicine,2003:127.
[26] Sousa R A;Reis R L;Cunha A M et al.Processing and properties of bone-analogue biodegradable and bioinert polymeric composites[J].Composites Science and Technology,2003,63:389.
[27] Reis R L;Cunha A M;Michael J B.Using nonconventional processing to develop anisotropic biodegradable composites of starch-based thermoplastics reinforced with bone-like ceramics[J].Medic Plast Biomater,1997:46.
[28] Reis R L;CunhaA M;Allan P S et al.Structure development and control of injection-molded hydroxylapatite-reinforced starch/EVOH composites[J].Advances in Polymer Technology,1997,4(16):263.
[29] Sousa R A;Mano J F;Reis R L et al.Mechanical performance of starch based bioactive composite biomaterials molded with preferred orientation[J].Polymer Engineering and Science,2002,5:1032.
[30] 贾崇明;贾颖.剪切控制取向注射成型概述[J].现代塑料加工应用,1997(06):24.
[31] Mano J F;Vaz M;Mendes S C.Dynamical mechanical properties of hydroxylapatite reinforced and porous starch-based degradable biomaterials[J].Journal of Materials Science:Materials in Medicine,1999:857.
[32] RODRIGUEZ L M;Mallet R M;Ferreira J M .Fabrication of porous hydroxyapatite bodies by a new direct consolidation method:starch consolidation[J].Journal of Biomedical Materials Research,2002,2:232.
[33] Lemos A F;Ferreira J M .Combining foaming and starch consolidation methods to develop macroporous HA implants[J].Key Engineering Materials,2004,6(254):1041.
[34] Vaz C. M,;Reis R L;Cunha A M.Improvement of Interfacial Interactions in Starch-EVOH/HA Composites[A].,1999:377.
[35] Vaz CM;Reis RL;Cunha AM .Use of coupling agents to enhance the interfacial interactions in starch-EVOH/hydroxylapatite composites.[J].Biomaterials,2002(2):629-635.
[36] Leonor IB;Ito A;Onuma K;Kanzaki N;Reis RL .In vitro bioactivity of starch thermoplastic/hydroxyapatite composite biomaterials: an in situ study using atomic force microscopy.[J].Biomaterials,2003(4):579-585.
[37] Vaz C M;Reis R L;Cunha A M.Degradation model of starch-EVOH+ HA composites[J].Materials Research Innovations,2001(04):375.
[38] 李玉宝.生物医学材料[M].北京:化学工业出版社,2003:265.
[39] 傅杰,李世普.生物可降解高分子材料及其在医学领域的应用(Ⅱ)[J].武汉工业大学学报,1999(05):19-22.
[40] 柯扬船;皮特·斯壮.聚合物-无机纳米复合材料[M].北京:化学工业出版社,2003:53.
[41] 姜永梅,姜萍,翁杰.羟基磷灰石(HA)表面改性对HA/聚乳酸复合材料力学性能的影响[J].功能材料,2004(z1):2424-2426,2430.
[42] 朱林杰,耿孝正,马秀清,李鹏.啮合同向双螺杆挤出过程聚合物熔融机理研究--螺纹元件组合中聚合物的熔融[J].中国塑料,2000(04):70-78.
上一张 下一张
上一张 下一张
计量
  • 下载量()
  • 访问量()
文章评分
  • 您的评分:
  • 1
    0%
  • 2
    0%
  • 3
    0%
  • 4
    0%
  • 5
    0%