赣南轻稀土高背景区和对照区人群血液生化指标检测结果显示, 两区人群血液诸多生化指标的总体均数有显著性差异. 与对照区相比, 轻稀土区人群具有血清总蛋白(TSP)、白蛋白(AL)、β-球蛋白(β-G)、谷丙转氨酶(GPT)、血清甘油三酯(STG)、免疫球蛋白A(IgA)等含量的总体均数降低以及胆固醇(CHO)含量总体均数升高的趋势, 而生化指标的显著性水平受稀土背景区生物链中稀土含量和稀土组成以及人群性别制约. 轻稀土背景区不同年龄段的人群血液中的某些生化指标总体均数, 如TSP含量显示出男性群体受稀土影响可能是一个单向不可逆的过程, 而女性群体则反映出受稀土影响后能产生自我修复的本能.
参考文献
[1] | HALEY T J;KOMESUN;FLESHER A M et al.Pharmacology and toxicity of terbium,thulium and ytterbium chlorides[J].Toxicology and Applied Pharmacology,1963,5:427-436. |
[2] | HALEY T J;KOMESUN;FLESHER A M et al.Pharmacology and toxicity of lutetium chloride[J].Journal of Pharmaceutical Sciences,1964,53:1186-1188. |
[3] | HALEY T J.Toxicity,in Handbook on the Physics and Chemistry of Rare Earths[M].Amsterdam:North-Holland,1979 |
[4] | HUTCHESON D P;GRAYDH;VERUGOPAL B et al.Nutritional safety of heavy metals in mice[J].Journal of Nutrition,1975,105:670-675. |
[5] | 麻慧贤;许鸣;李雨民.稀土硝酸盐对大鼠生化指标的影响[J].中国稀土学报,1985:85-89. |
[6] | GRACA J G;DAVISON F C;FEAVEL J B .Comparative toxicity of stable rare earth compounds.Ⅲ.Acute toxicity of intravenous injections of chlorides and chelates in dogs[J].Archives of Environmental Health,1964,8:555-564. |
[7] | EVANS C H.Biochemistry of the Lanthanides[M].New York:Plenum Press,1990:339-389. |
[8] | GABBIANI G;JACQMIN M L;RICHARD R M .Soft-tissue calcification induced by rare earth metals and its prevention by sodium pyrophosphate[J].British Journal of Pharmacology,1966,27:1-9. |
[9] | JOHANSSON O;PERRAULT G;SAVOIE L et al.Action of various metallic chlorides on calcaemia and phosphataemia[J].British Journal of Pharmacology and Chemotherapy,1968,33:91-97. |
[10] | GODIN D V;FROHLICH J .Erythrocyte alterations in praseodymium-induced lecithin: cholesterol acyltransferase (LCAT) deficiency in the rat: comparsion with familial LCAT deficiency in man[J].Research Communications in Chemical Pathology and Pharmacology,1981,31:555-556. |
[11] | MAGNUSSON G .The behavior of certain lanthanons in rats[J].Acta of Pharmacology and Toxicology,1963,20(z3):1-95. |
[12] | KADAS I;TANKA D;KELLER M et al.Enzyme-histochemical and biochemical study of liver injury induced by lanthanum trichloride[J].Acta Morphologica Academice Scientiarum Hungaricae,1974,22:35-45. |
[13] | SALAS M;TUCHWEBER B;KOVACS K et al.Effect of cerium on the rat liver: An ultrastructural and biochemical study[J].Beitr Pathol Biol,1976,157:23-44. |
[14] | KYKER G C;CRESS E A;SIBARAMAKRISHNAN V M et al.Fatty infiltration due to rare earths[J].Federation Proceedings,1957,16:207-209. |
[15] | SNYDER F;CRESS E A;KYKER G C .Rare-earth fatty liver[J].Nature,1960,A185:480-481. |
[16] | VONLEHNMANNB;OBERDISSE E;GRAJEWSKI O et al.Subcellar distribution of phospholipids during liver damage induced by rare earths[J].Archives of Toxicology,1975,34:89-101. |
[17] | RENAUD G;SOLER-ARGILAGA C;REY C et al.Free fatty acid mobilization in the development of cerium-induced fatty liver[J].Biochemical and Biophysical Research Communications,1980,92:374-380. |
[18] | ARVELA P;REINILA M;PELKONEN O .Effects of phenobarbital and β-naphthoflavone on cerium induced biochemical changes in rat serum[J].Toxicology Letters,1981,8:213-216. |
[19] | SCHURIG R;OBERDISSE E .The influence of rare earths on hepatic gluconeogenesis[J].Naunyn-Schmiedeberg's Archives of Pharmacology,1972,275:419-433. |
[20] | 张辉,冯嘉,朱为方.稀土高背景区生物链中稀土元素的分布特征[J].中国稀土学报,1999(04):365-368. |
[21] | 朱为方;徐素琴;邵萍萍 等.赣南稀土区生物效应研究-稀土日允许摄入量[J].中国环境科学,1997,17(01):63-66. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分:
-
10%
-
20%
-
30%
-
40%
-
50%