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The contraceptive efficacy and local effects of bioceramic IUD in rat were studied. The experiment was divided into four groups: bioceramic IUD group; stainless steel IUD group; operation control group; normal control group. All IUD samples were put into uterus of rats. The experimental results show that the alumina bioceramic has a strong contraceptive effect for those rats. In bioceramic IUD group the endometrial inflammation reaction was as mild as that in stainless IUD group during the early days (30 days ) and gradually abated with time during the late days (60 days ). The experiments show that the alumina bioceramic has a good biocompatibility and contraceptive effects and hint at the alumina bioceramic IUD may become a more safety reproduction family planning IUD.

参考文献

[1] Zhao Yongquan;Peng Dengren .Study on Effect of the Contraceptive LNGR-IUD on Endometrium and Main Organs in Rat[J].Peproduction & Contraception,1991,11(03):43-45.
[2] Zhu Dingshou;Wang Xingcui;Liu Xiaolan.The Contraceptive Efficacy and Local Effects of Different Tape of IUD inserted Female Rats[J].The Journal of Beijing Second Medical College,1981(03):214-217.
[3] Li Shipu;Chen Xiaoming.Bioceramics[M].武昌:武汉工业大学出版社,1989:10-24.
[4] Lu Zilan.The Theory and Practice of Family Planning[M].Shaoguan:Science and Technology Press,1989:204-206.
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