癌症是现代医学的难题,一直危害着人类的健康.放射治疗是癌症治疗的有效手段之一.由于重离子束在物理学和生物学性质上所具有的优势,它已成为放疗用的最佳射线.简述了重离子治癌的发展历程、现状以及特点,详细讨论了在医学物理和放射生物学研究领域值得关注的若干热点问题.
参考文献
| [1] | Wilson R R.Radiology,1946,47:487. |
| [2] | Ma Lin,Zhou Guixia,Feng Linchun.High LET(heavy ion and fast neutron)Malignant Tumors Therapeutic Radiology.Beijing:Military Medicine Science Press,2006,1-5(in Chinese).(马林,周桂霞,冯林春.恶性肿瘤高LET(重离子、快中子)放射治疗学.北京:军事医学科学出版社,2006,1-5.) |
| [3] | Available from:http://ptcog web psi.cn/. |
| [4] | Xiao Guoqing,Zhang Hong,Li Qiang,et al.Nuclear Physics Review,2007,24(2):85(in Chinese).(肖国青,张红,李强,等.原子核物理评论,2007,24(2):85.) |
| [5] | Kraft G.Nucl Instr and Meth,2000,A454:1. |
| [6] | Furursawa Y,Fukutsu K,Aoki M,et al.Radiat Res,2000,154:485. |
| [7] | Ledingham K W D,Galster W,Sauerbrey R.The British Journal of Radiology,2007,80:855. |
| [8] | Caporaso G J,Mackie T R,Sampayan S,et al.Physica Medica,2008,24(2):98. |
| [9] | Oliver J,Karger C P,Debus J.Med Phys,2008,35(12):5653. |
| [10] | Chatterjee A,Alpen E L,Llacer J,et al.Int J Radiat Oncol Biol Phys,1981,7:503. |
| [11] | Chatterjee A,Tobias C A,Lyman T J.Nuclear Fragmentation in Therapeutic and Diagnostic Studies with Heavy Ions.In:Shen B S P,Merker M ed.Spallation Nuclear Reactions with Their Applications.Dordrecht,Holland:D.Reidel,1978,169. |
| [12] | Lilzenberg D,Becehetti F,Brown D,et al.Positron Emission Tomogmphy of Implanted Radioactive Analog Radiotherapy Beams.In:Th Delbar ed.Proceedings of 2nd International Conference on Radioactive Nuclear Beams.Belgium:Adam Hilger Bristol,1992,423. |
| [13] | Tomitani T,Kanazawa M,Sudo M,et al.Beam and Point Measurement with Positron Emitting Secondary Beams.In;Ando K,Kanai T ed.Proceedings of the Third Workshop on Physical and Biological Research with Heavy Ions.China,Japan:National Institute of Radiologieal Sciences,1993,22. |
| [14] | Chatterjee A,Llacer J,Collier M,et al.Diagnosis Application of Radioactive Beams.In:Chu W T ed.Proceedings of the Fifth PTCOC Meeting and International Workshop on Biomedical Accelerators.Berkeley,California,USA:University of California,1986,213. |
| [15] | Henderson S D,Collier M,Renner T,et al.Med Phys,1987,14:468. |
| [16] | Collier J M,Henderson S D,Pitluck S,et al.Radiotherapy Physics.Annual Report 1986 of Biology and Medicine Division LBL.University of California.LBL-22300,1987,157. |
| [17] | Enghardt W,Fromm W D,Geissel H,et al.GSI Scientific Report 1992.1993,334. |
| [18] | Kanazawa M,Kitagawa A,Kouda S,et al.Nuclear Physics,2002,A701:244c. |
| [19] | Li Q,Kitagawa A,Kanai T,et al.Nucl Instrs and Meth,2004,13222:270. |
| [20] | Li Qiang,Wei Zengquan.Nuclear Technology,2002,25(1):71(in Chinese).(李强,卫增泉.核技术,2002,25(1):71.) |
| [21] | Li Q,Kanai T,Kitagawa A.Physics in Medicine and Biology,2003,48:2971. |
| [22] | Li Q,Furusawa Y,Kanazawa M,et al.Int J Radiat Oncol Biol Phys,2005,63:1237. |
| [23] | Li Q,Furusawa Y,Kanazawa M,et al.Chin Sci Bull,2005,50:2546. |
| [24] | Little J B.Oncogene,2003,22:6978. |
| [25] | Little J B.J Radiol Prot,2003,28:173. |
| [26] | Little J B.Int J Radiat Biol,1971,20:87. |
| [27] | Iyer R,Lehnert B E.Radiat Res,2002,157:3. |
| [28] | Sawant S G,Zheng W,Hopkins K M,et al.Radiation Re-search,2002.157:361. |
| [29] | Lyng F M,Seymour C B,Mothersill C.Radiation Research,2002,157:365. |
| [30] | Mothersill C,Seymour C.Int J Radiat Biol,1997,71:421. |
| [31] | Nagar A,Smith L E,Morgan W F.Cancer Res,2003,63:324. |
| [32] | Hamada N,Funayama T,Wada S,et al.Radiation Research,2006,166:24. |
| [33] | Tao Jiazun,Li Qiang,Wu Qingfeng.Nuclear Physics Review,2009,26(3):248(in Chinese).(陶家军,李强,吴庆丰.原子核物理评论,2009,26(3):248.) |
| [34] | Quintana E,Shackleton M,Sabel M S,et al.Nature,2008,456(4):593. |
| [35] | Cheng T,Rodrigues N,Shen H,et al.Science,2000,287:1804. |
| [36] | Yuan Y,Shen H,Franklin DS,et al.Nat Cell Biol,2004,6:436. |
| [37] | Kim C F,Dirks P B.Cell,2008,3(2):147. |
| [38] | Li F,Tiede B,Massagu J.Cell Research,2007,17(1):3. |
| [39] | Eyler C E,Rich J N,Clin J.Oncol,2008,26:2839. |
| [40] | Croker A K,Allan A L.J Cell Mol Med,2008,12(2):374. |
| [41] | Baumann M,Krause M,Hill R.Nat Rev Cancer,2008,8:545. |
| [42] | Bao S,Wu Q,McLendon R E,et al.Nature,2006,444:756. |
| [43] | Phillips T M,McBride W H,Pajonk F.J Natl Cancer Inst,2006,98:1777. |
| [44] | Diehn M,Cho R W,Lobo N A,et al.Nature,2009,458:780. |
| [45] | Moserle L,Ghisi M,Amadori A,et al.Cancer Lett,doi:10.1016/j.canlet.2009.05.020. |
| [46] | Sai S,Matsumoto Y,Furusawa Y,et al.Effect of Heavy Ion Radiation on Cancer Stem Cells of Xenograft Tumor in Nnude Mice.Proceedings of NIRS-IMP Joint Symposium on Carbon Iion Therapy.Lanzhou:Institute of Modern Physics,Chinese Academy of Sciences,2009,100. |
上一张
下一张
上一张
下一张
计量
- 下载量()
- 访问量()
文章评分
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%