Development of a PVA Hydrogel for Bioprosthetic Heart Valve Stent and Other Medical Applications

材料科学与工程学报, 2000, 18(z2): 988-992.

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1.Department of Chemical and Biochemical Engineering,London, Ontario;University of Western Ontario, The John Robarts Research Institute,London, Ontario

2.Department of Chemical and Biochemical Engineering,London, Ontario;University of Western Ontario, The John Robarts Research Institute,London, Ontario

3.Department of Chemical and Medical Biophysics,London,Ontario;Department of Chemical and Cardiology,London,Ontario;University of Western Ontario, The John Robarts Research Institute,London,Ontario

4.University of Western Ontario, The John Robarts Research Institute,London, Ontario;The University Campus, London Health Sciences Center, London, Ontario, Canada

5.Department of Chemical and Biochemical Engineering,London, Ontario;University of Western Ontario, The John Robarts Research Institute,London, Ontario

Development of a PVA Hydrogel for Bioprosthetic Heart Valve Stent and Other Medical Applications

Keywords： PVA hydrogel

Polyvinyl alcohol (PVA) hydrogel (15%w/w) was processed by freezing and thawing from one through six thermal cycles to obtain wide range of mechanical properties. The materials were tested under uniaxial tension and results show that matching mechanical properties to that of porcine aortic root can be achieved. A fatigue machine for elastomer materials and tissues was built and fatigue test on PVA sample was carried out. The test results show that the PVA has good fatigue property. The stent prototype was designed and successfully made by mold casting method. Some potential medical applications are discussed.

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Development of a PVA Hydrogel for Bioprosthetic Heart Valve Stent and Other Medical Applications

参考文献