羟基磷灰石骨水泥(HAC)的化学成分与人体骨组织的主要成分羟基磷灰石(HA)极为相似,在骨填充材料方面获得成功应用,但HAC结构稳定性高,植入生物体内长期不容易降解,作为骨组织工程修复材料使用受到限制.本文将HAC与锶、可降解生物纤维复合、调节钙磷比例、使HAC碳酸化以及改变固化液等提高HAC降解性的途径作出归纳,并就HAC降解性研究存在的问题和应用前景作出展望.
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